C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transcriptional regulator, SIN3A (yeast)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000042557 Sin3a 10090 + 9:57072040-57128366 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000049169 Sin3a-201 57086581-57128366 protein_coding
  ENSMUST00000163400 Sin3a-005 57076628-57095403 protein_coding
  ENSMUST00000165927 Sin3a-006 57095248-57097880 retained_intron
  ENSMUST00000167715 Sin3a-003 57075338-57128366 protein_coding
  ENSMUST00000167963 Sin3a-007 57113461-57125191 retained_intron
  ENSMUST00000168177 Sin3a-002 57076399-57128366 protein_coding
  ENSMUST00000168502 Sin3a-004 57081158-57128366 protein_coding
  ENSMUST00000168678 Sin3a-001 57076376-57128364 protein_coding
  ENSMUST00000169879 Sin3a-008 57072040-57089496 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000049169ENSMUST00000165927ENSMUST00000167715ENSMUST00000168177ENSMUST00000168678
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000049169 N/A N/A 7.314±0.00 N/A N/A N/A N/A N/A N/A N/A 2.697±0.78 11.794±0.00 10.323±1.46 N/A
ENSMUST00000165927 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 104.423±14.10 N/A N/A
ENSMUST00000167715 16.682±2.94 N/A 11.142±2.56 12.973±2.59 8.310±0.00 12.006±1.22 3.257±0.11 8.763±1.06 10.671±3.14 12.480±0.00 2.163±0.31 17.023±2.25 13.435±2.01 12.823±0.58
ENSMUST00000168177 N/A N/A N/A 3.263±0.00 N/A N/A 3.465±0.00 N/A 5.323±0.00 N/A 1.585±0.00 N/A N/A N/A
ENSMUST00000168678 7.689±0.87 23.431±5.49 N/A 10.643±1.93 18.160±7.44 N/A 3.870±1.30 N/A 5.202±0.51 10.157±0.00 1.666±0.00 20.121±2.13 5.393±1.29 11.889±0.27

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IGI negative regulation of transcription from RNA polymerase II promoter
GO:0000776 IDA kinetochore
GO:0000785 IEA chromatin
GO:0000976 IDA transcription regulatory region sequence-specific DNA binding
GO:0001102 IEA RNA polymerase II activating transcription factor binding
GO:0001103 IPI RNA polymerase II repressing transcription factor binding
GO:0001106 IGI RNA polymerase II transcription corepressor activity
GO:0001701 IMP in utero embryonic development
GO:0002218 IEA activation of innate immune response
GO:0002230 IEA positive regulation of defense response to virus by host
GO:0002244 IMP hematopoietic progenitor cell differentiation
GO:0003677 IDA DNA binding
GO:0003682 IDA chromatin binding
GO:0003700 IMP sequence-specific DNA binding transcription factor activity
GO:0003714 IDA transcription corepressor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 IPI transcription factor complex
GO:0005737 IEA cytoplasm
GO:0006260 IMP DNA replication
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0006476 IEA protein deacetylation
GO:0007568 IEA aging
GO:0008134 IPI transcription factor binding
GO:0010243 IEA response to organonitrogen compound
GO:0010971 IMP positive regulation of G2/M transition of mitotic cell cycle
GO:0016580 IEA Sin3 complex
GO:0017053 IPI:IDA transcriptional repressor complex
GO:0031937 IEA positive regulation of chromatin silencing
GO:0032403 IEA protein complex binding
GO:0033558 IEA protein deacetylase activity
GO:0034613 IMP cellular protein localization
GO:0042754 IMP negative regulation of circadian rhythm
GO:0043066 IMP negative regulation of apoptotic process
GO:0043234 IEA protein complex
GO:0043619 IEA regulation of transcription from RNA polymerase II promoter in response to oxidative stress
GO:0045171 IEA intercellular bridge
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0048511 IEA rhythmic process
GO:0051595 IDA response to methylglyoxal
GO:0071333 IDA cellular response to glucose stimulus
GO:1900181 IEA negative regulation of protein localization to nucleus
GO:1901675 IEA negative regulation of histone H3-K27 acetylation
GO:2000678 IEA negative regulation of transcription regulatory region DNA binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000059812 sin3ab SIN3 homolog A, transcription regulator (yeast) b protein_coding Danio_rerio
ENSDARG00000079716 sin3aa SIN3 homolog A, transcription regulator (yeast) a protein_coding Danio_rerio
ENSG00000169375 SIN3A SIN3 transcription regulator family member A protein_coding Homo_sapiens

Loading