C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: zinc finger E-box binding homeobox 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169554 ZEB2 9606 - 2:144388001-144524580 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000303660 ZEB2-020 144388013-144520002 protein_coding
  ENST00000392861 ZEB2-007 144399870-144518261 protein_coding
  ENST00000409211 ZEB2-019 144424792-144518406 protein_coding
  ENST00000409487 ZEB2-011 144388001-144517730 protein_coding
  ENST00000419938 ZEB2-013 144388013-144430026 protein_coding
  ENST00000427902 ZEB2-010 144399080-144517718 protein_coding
  ENST00000431672 ZEB2-008 144424817-144517548 protein_coding
  ENST00000434448 ZEB2-018 144429769-144518406 processed_transcript
  ENST00000435831 ZEB2-021 144429826-144517897 protein_coding
  ENST00000440875 ZEB2-201 144397819-144520391 protein_coding
  ENST00000444559 ZEB2-014 144429911-144520399 protein_coding
  ENST00000453352 ZEB2-017 144429826-144520119 processed_transcript
  ENST00000461784 ZEB2-016 144429556-144517583 retained_intron
  ENST00000462355 ZEB2-022 144513423-144517649 protein_coding
  ENST00000464380 ZEB2-003 144517351-144520649 processed_transcript
  ENST00000465070 ZEB2-005 144511385-144520332 protein_coding
  ENST00000465308 ZEB2-004 144428047-144520340 retained_intron
  ENST00000470879 ZEB2-009 144511385-144517755 protein_coding
  ENST00000472146 ZEB2-006 144426805-144520119 retained_intron
  ENST00000475115 ZEB2-002 144517351-144524580 processed_transcript
  ENST00000476394 ZEB2-015 144429603-144520386 retained_intron
  ENST00000479735 ZEB2-024 144429788-144516761 processed_transcript
  ENST00000484313 ZEB2-012 144462183-144517419 processed_transcript
  ENST00000497268 ZEB2-027 144403995-144405373 retained_intron
  ENST00000539609 ZEB2-025 144388009-144520119 protein_coding
  ENST00000558170 ZEB2-001 144388016-144520313 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000303660ENST00000392861ENST00000409487ENST00000419938ENST00000427902ENST00000470879ENST00000472146ENST00000539609
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000303660 15.861±0.00 12.738±0.00 8.422±0.00 13.469±5.52 11.072±3.96 6.260±1.95 6.654±1.17 4.169±0.55 12.031±10.23 12.880±0.93 1.495±0.17 9.504±4.18 4.890±0.74 6.634±5.26
ENST00000392861 N/A N/A N/A N/A N/A N/A 7.629±0.00 N/A N/A N/A 3.778±0.00 N/A N/A N/A
ENST00000409487 N/A N/A N/A N/A 3.459±0.00 4.626±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000419938 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.443±0.00 N/A N/A
ENST00000427902 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.614±0.00 N/A N/A N/A
ENST00000470879 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.090±0.00 N/A
ENST00000472146 N/A N/A N/A N/A 4.783±0.00 N/A N/A N/A N/A 8.513±0.00 N/A 4.734±0.00 N/A N/A
ENST00000539609 N/A N/A N/A 9.730±0.00 N/A N/A N/A N/A N/A N/A N/A 0.552±0.00 1.887±0.74 2.388±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007L9 CIL_0007L9_0003 UCNEbase 2:143915206-145198080
CIL_0006M9 CIL_0006M9_0001 CGP 2:143938068-144524580
CIL_0008S1 CIL_0008S1_0001 VISTA 2:144130532-144732245
CIL_0008RV CIL_0008RV_0001 VISTA 2:144143079-144743846
CIL_000944 CIL_000944_0001 VISTA 2:144209700-144811716
CIL_0008FM CIL_0008FM_0001 VISTA 2:144282035-144883963
CIL_0007GY CIL_0007GY_0001 CGP 2:144388001-147930826

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IMP negative regulation of transcription from RNA polymerase II promoter
GO:0001755 IEA neural crest cell migration
GO:0001756 IEA somitogenesis
GO:0001843 IEA neural tube closure
GO:0003676 IEA nucleic acid binding
GO:0003677 IEA DNA binding
GO:0005634 IEA:IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0007399 NAS nervous system development
GO:0007417 IEA central nervous system development
GO:0019208 NAS phosphatase regulator activity
GO:0021766 IEA hippocampus development
GO:0021846 IEA cell proliferation in forebrain
GO:0030177 IEA positive regulation of Wnt signaling pathway
GO:0043507 IEA positive regulation of JUN kinase activity
GO:0045636 ISS positive regulation of melanocyte differentiation
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0048023 IC positive regulation of melanin biosynthetic process
GO:0048066 ISS developmental pigmentation
GO:0048598 IEA embryonic morphogenesis
GO:0070412 IEA R-SMAD binding
GO:0097324 ISS melanocyte migration
GO:1903056 ISS regulation of melanosome organization

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078416 zeb2b zinc finger E-box binding homeobox 2b protein_coding Danio_rerio
ENSMUSG00000026872 Zeb2 zinc finger E-box binding homeobox 2 protein_coding Mus_musculus

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