C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM and senescent cell antigen-like domains 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169756 LIMS1 9606 + 2:108534355-108687246 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000332345 LIMS1-002 108588311-108684137 protein_coding
  ENST00000338045 LIMS1-014 108654812-108684448 protein_coding
  ENST00000393310 LIMS1-001 108588466-108687246 protein_coding
  ENST00000409441 LIMS1-003 108621266-108684448 protein_coding
  ENST00000410093 LIMS1-006 108607161-108684448 protein_coding
  ENST00000414829 LIMS1-005 108655053-108662303 nonsense_mediated_decay
  ENST00000422797 LIMS1-004 108621273-108673953 nonsense_mediated_decay
  ENST00000428064 LIMS1-007 108534456-108673029 protein_coding
  ENST00000434274 LIMS1-011 108657894-108662800 nonsense_mediated_decay
  ENST00000449684 LIMS1-008 108621251-108670815 processed_transcript
  ENST00000462817 LIMS1-009 108655012-108660313 processed_transcript
  ENST00000474038 LIMS1-010 108654919-108659945 retained_intron
  ENST00000480744 LIMS1-012 108675877-108681012 processed_transcript
  ENST00000496653 LIMS1-013 108655016-108671005 retained_intron
  ENST00000542845 LIMS1-201 108654812-108687238 protein_coding
  ENST00000544547 LIMS1-202 108534355-108687238 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000332345ENST00000393310ENST00000409441ENST00000410093ENST00000542845ENST00000544547
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000332345 N/A N/A 1.379±0.00 N/A N/A 2.986±0.00 N/A N/A N/A N/A N/A 6.243±0.00 N/A 3.443±0.00
ENST00000393310 N/A N/A N/A 0.735±0.00 1.664±0.00 N/A N/A N/A N/A N/A N/A 1.356±0.11 1.214±0.00 N/A
ENST00000409441 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.370±0.00 N/A N/A N/A N/A
ENST00000410093 N/A N/A N/A 1.012±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000542845 N/A N/A N/A N/A N/A N/A N/A N/A 1.633±0.00 N/A N/A N/A N/A N/A
ENST00000544547 13.736±0.00 8.792±0.00 0.447±0.00 3.904±0.00 5.463±3.78 5.658±3.83 6.663±0.00 6.432±0.00 3.693±0.35 9.711±8.57 8.417±0.00 5.526±3.22 7.965±1.41 6.064±2.85

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RA CIL_0007RA_0001 VISTA 2:108335931-108937600
CIL_00010T CIL_00010T_0001 CGP 2:108448561-108687246
CIL_00010W CIL_00010W_0001 CGP 2:108534355-108785811

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005911 IMP cell-cell junction
GO:0005925 IDA focal adhesion
GO:0007160 IEA cell-matrix adhesion
GO:0007163 IEA establishment or maintenance of cell polarity
GO:0007569 TAS cell aging
GO:0008270 IDA:IEA zinc ion binding
GO:0010628 IMP positive regulation of gene expression
GO:0010811 IMP positive regulation of cell-substrate adhesion
GO:0016337 IEA single organismal cell-cell adhesion
GO:0019901 IPI protein kinase binding
GO:0034329 TAS cell junction assembly
GO:0043009 IEA chordate embryonic development
GO:0043066 IEA negative regulation of apoptotic process
GO:0043234 IEA protein complex
GO:0043547 IMP positive regulation of GTPase activity
GO:0045184 IMP establishment of protein localization
GO:0045216 IEA cell-cell junction organization
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0048471 IDA perinuclear region of cytoplasm
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0051291 IEA protein heterooligomerization
GO:0051894 IMP positive regulation of focal adhesion assembly
GO:0071560 IEP cellular response to transforming growth factor beta stimulus
GO:1900026 IMP positive regulation of substrate adhesion-dependent cell spreading
GO:2000178 IEA negative regulation of neural precursor cell proliferation
GO:2000346 IEA negative regulation of hepatocyte proliferation
GO:2001046 IEA positive regulation of integrin-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000019920 Lims1 LIM and senescent cell antigen-like domains 1 protein_coding Mus_musculus

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