C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM and senescent cell antigen-like domains 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000019920 Lims1 10090 + 10:58323466-58424691 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020077 Lims1-002 58394373-58421783 protein_coding
  ENSMUST00000020078 Lims1-001 58323466-58424691 protein_coding
  ENSMUST00000105468 Lims1-003 58394388-58421578 protein_coding
  ENSMUST00000124312 Lims1-004 58408057-58410336 processed_transcript
  ENSMUST00000148799 Lims1-005 58416643-58421664 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020078ENSMUST00000105468ENSMUST00000148799
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020078 16.505±5.67 5.053±0.67 20.350±2.39 6.191±3.81 9.104±1.12 10.649±2.09 5.950±1.94 7.772±1.13 9.919±8.52 27.502±2.29 1.577±0.70 17.745±7.02 17.293±7.09 2.702±1.45
ENSMUST00000105468 7.143±0.00 N/A N/A N/A 3.389±0.08 4.891±1.81 8.933±0.00 3.040±0.24 N/A 12.473±1.96 N/A 9.277±1.40 N/A 4.010±1.01
ENSMUST00000148799 N/A N/A N/A 3.403±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 18.534±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RA CIL_0007RA_0002 VISTA 10:58082278-58683620
CIL_00010T CIL_00010T_0002 CGP 10:58255497-58424691
CIL_00010W CIL_00010W_0002 CGP 10:58323466-58494155

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005886 IEA plasma membrane
GO:0005911 IEA cell-cell junction
GO:0005925 IDA focal adhesion
GO:0007160 IMP cell-matrix adhesion
GO:0007163 IMP establishment or maintenance of cell polarity
GO:0008270 IEA zinc ion binding
GO:0010628 IEA positive regulation of gene expression
GO:0010811 IEA positive regulation of cell-substrate adhesion
GO:0016337 IMP single organismal cell-cell adhesion
GO:0019901 IEA protein kinase binding
GO:0043009 IMP chordate embryonic development
GO:0043066 IGI negative regulation of apoptotic process
GO:0043234 IEA protein complex
GO:0043547 IEA positive regulation of GTPase activity
GO:0045184 IEA establishment of protein localization
GO:0045216 IGI cell-cell junction organization
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0048471 IEA perinuclear region of cytoplasm
GO:0050680 IGI negative regulation of epithelial cell proliferation
GO:0051291 IEA protein heterooligomerization
GO:0051894 IEA positive regulation of focal adhesion assembly
GO:0071560 IEA cellular response to transforming growth factor beta stimulus
GO:1900026 IEA positive regulation of substrate adhesion-dependent cell spreading
GO:2000178 IGI negative regulation of neural precursor cell proliferation
GO:2000346 IGI negative regulation of hepatocyte proliferation
GO:2001046 IGI positive regulation of integrin-mediated signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000169756 LIMS1 LIM and senescent cell antigen-like domains 1 protein_coding Homo_sapiens

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