C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin, alpha M (complement component 3 receptor 3 subunit)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000169896 ITGAM 9606 + 16:31259990-31332892 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000287497 ITGAM-002 31259990-31331768 protein_coding
  ENST00000544665 ITGAM-001 31259994-31332892 protein_coding
  ENST00000561838 ITGAM-005 31324678-31326968 retained_intron
  ENST00000565142 ITGAM-008 31330380-31331536 protein_coding
  ENST00000567031 ITGAM-003 31275592-31324439 protein_coding
  ENST00000567178 ITGAM-007 31328037-31329905 retained_intron
  ENST00000569746 ITGAM-006 31329002-31330052 retained_intron
  ENST00000570242 ITGAM-004 31271885-31273684 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000287497ENST00000544665
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000287497 N/A 0.100±0.00 0.453±0.00 1.065±0.00 0.313±0.00 0.125±0.00 0.743±0.00 N/A N/A N/A N/A 2.448±0.00 0.443±0.00
ENST00000544665 2.835±0.00 0.050±0.00 N/A 1.069±0.00 1.398±0.00 0.195±0.00 0.614±0.00 0.880±0.00 5.790±0.00 0.054±0.00 0.823±0.52 1.994±0.91 1.177±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00035O CIL_00035O_0001 CGP 16:31259990-31382997

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001846 IEA opsonin binding
GO:0001948 IPI glycoprotein binding
GO:0002224 TAS toll-like receptor signaling pathway
GO:0002523 IEA leukocyte migration involved in inflammatory response
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005886 TAS plasma membrane
GO:0007155 TAS cell adhesion
GO:0007159 IEA leukocyte cell-cell adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0007596 TAS blood coagulation
GO:0008201 IEA heparin binding
GO:0008305 IEA integrin complex
GO:0009897 IEA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0010668 IEP ectodermal cell differentiation
GO:0014005 IEA microglia development
GO:0016021 IEA integral component of membrane
GO:0016337 IEA single organismal cell-cell adhesion
GO:0030198 TAS extracellular matrix organization
GO:0030593 IEA neutrophil chemotaxis
GO:0034142 TAS toll-like receptor 4 signaling pathway
GO:0043395 IEA heparan sulfate proteoglycan binding
GO:0045087 TAS innate immune response
GO:0045123 IEA cellular extravasation
GO:0046872 IEA metal ion binding
GO:0046982 IEA protein heterodimerization activity
GO:0050798 IEA activated T cell proliferation
GO:0050900 TAS leukocyte migration
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002956 ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) protein_coding Danio_rerio
ENSMUSG00000030786 Itgam integrin alpha M protein_coding Mus_musculus

Loading