C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: integrin alpha M
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000030786 Itgam 10090 + 7:128062640-128128160 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000064821 Itgam-004 128062640-128118490 protein_coding
  ENSMUST00000098015 Itgam-001 128062683-128128160 protein_coding
  ENSMUST00000106240 Itgam-002 128062683-128117531 protein_coding
  ENSMUST00000106242 Itgam-201 128062647-128118491 protein_coding
  ENSMUST00000119696 Itgam-008 128062728-128070615 protein_coding
  ENSMUST00000120355 Itgam-003 128062679-128117090 protein_coding
  ENSMUST00000126475 Itgam-007 128070659-128118490 protein_coding
  ENSMUST00000134694 Itgam-010 128116436-128127216 protein_coding
  ENSMUST00000156593 Itgam-009 128062743-128070857 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000064821ENSMUST00000098015ENSMUST00000106240ENSMUST00000106242ENSMUST00000119696ENSMUST00000120355ENSMUST00000126475ENSMUST00000134694
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000064821 3.417±0.80 1.111±0.62 2.082±0.20 0.173±0.10 4.665±1.71 1.347±0.36 0.608±0.21 0.368±0.18 2.173±2.43 3.441±0.88 0.099±0.00 1.799±0.89 0.440±0.49 0.177±0.07
ENSMUST00000098015 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.030±0.00 N/A N/A N/A
ENSMUST00000106240 2.698±0.13 N/A N/A 0.151±0.00 7.017±4.01 0.912±0.11 0.502±0.16 0.338±0.07 0.107±0.04 1.330±0.16 0.071±0.02 1.455±0.47 0.105±0.00 0.041±0.00
ENSMUST00000106242 1.401±0.40 1.328±0.06 1.404±0.64 0.189±0.10 3.446±1.15 1.199±0.39 0.412±0.10 0.503±0.21 1.180±1.46 1.272±0.33 0.175±0.08 1.547±0.64 0.290±0.33 N/A
ENSMUST00000119696 N/A N/A N/A N/A N/A N/A N/A N/A 0.748±0.00 N/A N/A N/A N/A N/A
ENSMUST00000120355 1.827±0.00 0.276±0.00 N/A N/A N/A N/A N/A N/A 0.079±0.04 1.789±0.00 0.031±0.00 0.747±0.00 N/A N/A
ENSMUST00000126475 N/A N/A 0.659±0.00 1.486±0.00 2.738±0.00 N/A N/A N/A 0.085±0.00 N/A 0.262±0.21 1.605±0.35 0.300±0.26 0.213±0.00
ENSMUST00000134694 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.388±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00035O CIL_00035O_0002 CGP 7:128062640-128150656

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001846 IDA opsonin binding
GO:0001948 IEA glycoprotein binding
GO:0002523 IMP leukocyte migration involved in inflammatory response
GO:0003735 IEA structural constituent of ribosome
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005840 IEA ribosome
GO:0006412 IEA translation
GO:0007155 IMP cell adhesion
GO:0007159 IMP leukocyte cell-cell adhesion
GO:0007229 IEA integrin-mediated signaling pathway
GO:0008201 IDA heparin binding
GO:0008305 IEA integrin complex
GO:0009897 IDA external side of plasma membrane
GO:0009986 IDA cell surface
GO:0010668 IEA ectodermal cell differentiation
GO:0014005 IDA microglia development
GO:0016021 IDA integral component of membrane
GO:0016337 IGI single organismal cell-cell adhesion
GO:0030593 IMP neutrophil chemotaxis
GO:0043395 IDA heparan sulfate proteoglycan binding
GO:0045123 IMP cellular extravasation
GO:0046872 IEA metal ion binding
GO:0046982 IEA protein heterodimerization activity
GO:0050798 IMP activated T cell proliferation
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002956 ITGAX integrin, alpha X (complement component 3 receptor 4 subunit) protein_coding Danio_rerio
ENSG00000169896 ITGAM integrin, alpha M (complement component 3 receptor 3 subunit) protein_coding Homo_sapiens

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