C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ubiquitin specific peptidase 47
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170242 USP47 9606 + 11:11841423-11959323 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000305481 USP47-005 11950443-11959154 processed_transcript
  ENST00000339865 USP47-001 11841423-11959323 protein_coding
  ENST00000399455 USP47-003 11842066-11959323 protein_coding
  ENST00000525078 USP47-006 11938330-11943149 retained_intron
  ENST00000525257 USP47-013 11841940-11884499 processed_transcript
  ENST00000525367 USP47-008 11880186-11884705 retained_intron
  ENST00000527733 USP47-002 11841975-11956421 protein_coding
  ENST00000529813 USP47-004 11950873-11956945 retained_intron
  ENST00000530041 USP47-009 11943427-11949975 processed_transcript
  ENST00000530369 USP47-010 11948024-11952777 retained_intron
  ENST00000531513 USP47-011 11942950-11949074 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000305481ENST00000339865ENST00000399455ENST00000525078ENST00000527733
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000305481 3.093±0.00 3.197±0.00 N/A 3.589±1.03 2.996±0.00 3.662±0.00 2.432±0.00 4.173±0.00 2.906±0.00 2.505±0.00 7.859±0.00 5.655±0.00 2.673±0.69 8.347±0.00
ENST00000339865 1.201±0.00 N/A 0.637±0.00 4.891±0.00 0.970±0.00 1.027±0.00 1.203±0.00 1.009±0.06 1.321±0.00 1.342±0.00 N/A 2.825±1.59 3.020±0.00 N/A
ENST00000399455 N/A N/A 1.238±0.00 3.291±0.00 1.806±0.00 N/A 2.802±1.55 0.795±0.00 N/A 2.599±0.00 3.973±0.12 N/A N/A N/A
ENST00000525078 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 16.244±0.00 14.021±0.00 N/A
ENST00000527733 9.439±0.00 7.992±0.00 3.757±0.00 3.076±0.47 7.617±0.59 7.253±0.37 4.254±1.32 6.196±0.33 7.187±1.89 7.000±0.62 8.863±7.71 8.910±4.08 9.196±6.28 24.800±12.26

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001HU CIL_0001HU_0002 CGP 11:11841423-12009769

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004843 IDA ubiquitin-specific protease activity
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0006284 IMP base-excision repair
GO:0006511 IEA ubiquitin-dependent protein catabolic process
GO:0006974 IMP cellular response to DNA damage stimulus
GO:0010972 IMP negative regulation of G2/M transition of mitotic cell cycle
GO:0019005 IDA SCF ubiquitin ligase complex
GO:0030307 IMP positive regulation of cell growth
GO:0034644 ISS cellular response to UV
GO:0035520 IDA monoubiquitinated protein deubiquitination
GO:0036459 IEA ubiquitinyl hydrolase activity
GO:0042493 IMP response to drug
GO:0043066 IMP negative regulation of apoptotic process
GO:0043154 IMP negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0045892 IMP negative regulation of transcription, DNA-templated
GO:0071987 IPI WD40-repeat domain binding
GO:1902230 IEA negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088890 usp47 ubiquitin specific peptidase 47 protein_coding Danio_rerio
ENSMUSG00000059263 Usp47 ubiquitin specific peptidase 47 protein_coding Mus_musculus

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