C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ring finger protein 34, E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170633 RNF34 9606 + 12:121400041-121430623 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000361234 RNF34-001 121400041-121424351 protein_coding
  ENST00000392464 RNF34-005 121400144-121430623 protein_coding
  ENST00000392465 RNF34-002 121400119-121424348 protein_coding
  ENST00000553407 RNF34-003 121400129-121418740 retained_intron
  ENST00000554484 RNF34-004 121419898-121424349 retained_intron
  ENST00000554606 RNF34-006 121400142-121417789 protein_coding
  ENST00000554868 RNF34-009 121409455-121417521 protein_coding
  ENST00000555076 RNF34-008 121400147-121423906 protein_coding
  ENST00000556562 RNF34-007 121400128-121416609 retained_intron
  ENST00000557402 RNF34-010 121409475-121416286 protein_coding
  ENST00000613529 RNF34-201 121400083-121424352 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000361234ENST00000392465ENST00000554484ENST00000613529
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000361234 4.924±0.00 1.396±0.00 10.301±0.62 6.834±0.41 4.825±0.74 5.217±2.73 4.288±1.68 4.204±1.91 6.259±0.55 10.590±6.73 11.742±5.10 8.478±3.05 11.303±1.17
ENST00000392465 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 8.382±0.00
ENST00000554484 N/A 1.359±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000613529 2.866±0.00 N/A 8.489±0.00 N/A 6.067±0.00 N/A 4.209±0.00 2.105±0.00 N/A N/A N/A N/A 9.517±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007G3 CIL_0007G3_0002 CGP 12:121308245-121430623
CIL_0007G4 CIL_0007G4_0002 CGP 12:121400041-121581015

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002039 IPI p53 binding
GO:0004842 IEA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005886 IDA plasma membrane
GO:0008270 IEA zinc ion binding
GO:0016567 IDA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0031625 IPI ubiquitin protein ligase binding
GO:0035872 IMP nucleotide-binding domain, leucine rich repeat containing receptor signaling pathway
GO:0042787 IMP protein ubiquitination involved in ubiquitin-dependent protein catabolic process
GO:0043161 IDA proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0061630 IDA ubiquitin protein ligase activity
GO:0070417 IEA cellular response to cold
GO:0070936 IMP protein K48-linked ubiquitination
GO:1901797 IMP negative regulation of signal transduction by p53 class mediator
GO:1901981 IDA phosphatidylinositol phosphate binding
GO:1902042 IMP negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:2000374 ISS regulation of oxygen metabolic process
GO:2001271 IMP negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038300 rnf34a ring finger protein 34a protein_coding Danio_rerio
ENSDARG00000054036 rnf34b ring finger protein 34b protein_coding Danio_rerio
ENSMUSG00000029474 Rnf34 ring finger protein 34 protein_coding Mus_musculus

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