C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protein phosphatase, Mg2+/Mn2+ dependent, 1D
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000170836 PPM1D 9606 + 17:60600183-60666280 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000305921 PPM1D-001 60600183-60666280 protein_coding
  ENST00000392995 PPM1D-002 60600269-60664473 nonsense_mediated_decay
  ENST00000590418 PPM1D-004 60604594-60633957 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000305921ENST00000392995ENST00000590418
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000305921 1.537±0.00 1.206±0.00 0.428±0.00 0.868±0.41 1.296±0.00 0.957±0.37 0.670±0.00 1.129±0.00 0.496±0.30 1.000±0.45 0.902±0.00 1.925±1.10 1.610±0.46 2.947±0.00
ENST00000392995 1.970±0.00 1.905±0.00 0.299±0.00 1.067±0.21 1.971±0.59 1.952±0.89 1.303±0.47 2.716±0.62 0.926±0.43 1.470±0.32 1.793±0.00 2.795±1.12 4.765±0.83 8.835±3.00
ENST00000590418 N/A N/A 1.711±0.00 N/A N/A 3.012±0.00 N/A N/A N/A 2.430±0.00 N/A N/A N/A 9.337±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000704 CIL_000704_0001 CGP 17:60443149-60666280
CIL_000569 CIL_000569_0002 CGP 17:60600183-61392838

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000086 IEA G2/M transition of mitotic cell cycle
GO:0003824 IEA catalytic activity
GO:0004722 IDA protein serine/threonine phosphatase activity
GO:0005515 IPI protein binding
GO:0005634 TAS nucleus
GO:0006470 TAS protein dephosphorylation
GO:0008152 IEA metabolic process
GO:0008285 TAS negative regulation of cell proliferation
GO:0009314 TAS response to radiation
GO:0009617 IEA response to bacterium
GO:0035970 IDA peptidyl-threonine dephosphorylation
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000009273 ppm1da protein phosphatase 1D magnesium-dependent, delta isoform a protein_coding Danio_rerio
ENSDARG00000021380 ppm1db protein phosphatase 1D magnesium-dependent, delta isoform b protein_coding Danio_rerio
ENSMUSG00000020525 Ppm1d protein phosphatase 1D magnesium-dependent, delta isoform protein_coding Mus_musculus

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