C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: potassium channel, subfamily K, member 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000171303 KCNK3 9606 + 2:26692690-26733420 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000302909 KCNK3-001 26692751-26733420 protein_coding
  ENST00000620977 KCNK3-201 26692690-26729255 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000302909ENST00000620977
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000302909 0.269±0.00 2.962±0.00 0.095±0.00 0.606±0.00 0.273±0.00 0.713±0.00 0.173±0.15 0.488±0.00 0.136±0.00 14.013±0.00 0.034±0.00 1.408±1.70 8.183±0.00 0.609±0.44
ENST00000620977 N/A N/A N/A N/A 0.554±0.00 N/A 0.524±0.38 N/A 0.339±0.00 N/A 0.251±0.00 5.302±0.00 18.475±6.19 0.121±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007WF CIL_0007WF_0001 VISTA 2:26419781-27023232
CIL_00004M CIL_00004M_0001 CGP 2:26581202-26733420
CIL_00004N CIL_00004N_0001 CGP 2:26692690-26781231

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005216 IMP ion channel activity
GO:0005252 IEA open rectifier potassium channel activity
GO:0005267 TAS:IEA potassium channel activity
GO:0005515 IEA protein binding
GO:0005886 IMP plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006813 TAS potassium ion transport
GO:0007268 TAS synaptic transmission
GO:0007420 IEA brain development
GO:0008022 IEA protein C-terminus binding
GO:0016020 IEA membrane
GO:0022841 IDA potassium ion leak channel activity
GO:0034220 IMP ion transmembrane transport
GO:0034765 IEA regulation of ion transmembrane transport
GO:0042493 IEA response to drug
GO:0042803 IEA protein homodimerization activity
GO:0044548 IPI S100 protein binding
GO:0046982 IEA protein heterodimerization activity
GO:0051481 IEA negative regulation of cytosolic calcium ion concentration
GO:0071294 IEA cellular response to zinc ion
GO:0071456 IEA cellular response to hypoxia
GO:0071805 IEA potassium ion transmembrane transport
GO:0090102 IEA cochlea development

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043466 kcnk3 potassium channel, subfamily K, member 3 protein_coding Danio_rerio
ENSDARG00000052898 KCNK3 (2 of 2) potassium channel, subfamily K, member 3 protein_coding Danio_rerio
ENSMUSG00000049265 Kcnk3 potassium channel, subfamily K, member 3 protein_coding Mus_musculus

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