C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: kinase suppressor of ras 2
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000425217 KSR2-201 ENSG00000171435 9606 - 12:117453012-117968223 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBrainHeartKidneyLungMuscleOvaryPlacentaTestisENST00000425217
Transcript ID Adipose Brain Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000425217 0.003±0.00 0.313±0.00 0.005±0.00 0.003±0.00 0.015±0.00 0.002±0.00 0.006±0.00 0.005±0.00 0.130±0.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0001QM CIL_0001QM_0002 CGP 12:117208142-117968983

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005078 IEA MAP-kinase scaffold activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005829 IEA cytosol
GO:0005886 IEA plasma membrane
GO:0006468 IEA protein phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019722 IEA calcium-mediated signaling
GO:0031434 IEA mitogen-activated protein kinase kinase binding
GO:0035556 IEA intracellular signal transduction
GO:0043410 IEA positive regulation of MAPK cascade
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000180430 Ksr2-001 protein_coding Mus_musculus 0 3448
ENSDART00000125291 ksr2-001 protein_coding Danio_rerio 0 1075
ENSMUST00000073347 Ksr2-002 retained_intron Mus_musculus 0 1011
ENSMUST00000018478 Ksr1-001 protein_coding Mus_musculus 0 398
ENSDART00000147300 ksr2-002 processed_transcript Danio_rerio 6e-36 159

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