C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: RAS guanyl releasing protein 1 (calcium and DAG-regulated)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000172575 RASGRP1 9606 - 15:38488103-38565575 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000310803 RASGRP1-001 38488103-38564806 protein_coding
  ENST00000414708 RASGRP1-004 38490554-38564635 nonsense_mediated_decay
  ENST00000450598 RASGRP1-005 38490554-38564635 protein_coding
  ENST00000539159 RASGRP1-201 38488105-38564806 protein_coding
  ENST00000557875 RASGRP1-012 38494452-38501190 nonsense_mediated_decay
  ENST00000558164 RASGRP1-006 38490554-38564635 protein_coding
  ENST00000558418 RASGRP1-010 38518381-38560279 protein_coding
  ENST00000558432 RASGRP1-007 38490095-38560082 protein_coding
  ENST00000559830 RASGRP1-003 38490554-38564635 protein_coding
  ENST00000560425 RASGRP1-011 38498916-38511705 nonsense_mediated_decay
  ENST00000560929 RASGRP1-009 38526384-38565169 protein_coding
  ENST00000561117 RASGRP1-008 38526309-38565239 protein_coding
  ENST00000561180 RASGRP1-002 38490480-38565575 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonKidneyLiverLungMuscleOvaryPlacentaTestisENST00000310803ENST00000450598ENST00000539159ENST00000557875ENST00000558164ENST00000558418ENST00000558432ENST00000559830ENST00000560425ENST00000561180
Transcript ID Adrenal Bladder Brain Breast Colon Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000310803 0.754±0.00 N/A 1.464±0.00 1.330±0.00 0.035±0.00 1.787±0.00 0.033±0.00 0.269±0.00 N/A 0.108±0.07 0.352±0.23 0.535±0.00
ENST00000450598 N/A N/A 3.352±0.00 N/A N/A N/A N/A 1.147±0.00 N/A N/A N/A 1.226±0.00
ENST00000539159 N/A N/A N/A N/A 0.082±0.00 N/A N/A N/A N/A 0.063±0.00 0.182±0.00 N/A
ENST00000557875 N/A N/A N/A N/A N/A 0.821±0.00 N/A N/A N/A N/A N/A N/A
ENST00000558164 N/A N/A N/A N/A 0.712±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000558418 N/A N/A N/A N/A N/A N/A 0.104±0.00 N/A N/A N/A N/A N/A
ENST00000558432 N/A 0.868±0.00 2.533±0.00 N/A N/A N/A 0.409±0.00 N/A N/A 0.154±0.00 N/A N/A
ENST00000559830 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.260±0.00 N/A N/A
ENST00000560425 N/A N/A N/A N/A N/A N/A N/A N/A 0.603±0.00 N/A N/A N/A
ENST00000561180 N/A 0.901±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.210±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002RQ CIL_0002RQ_0001 CGP 15:38454127-38565575

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001816 IEA cytokine production
GO:0002437 IEA inflammatory response to antigenic stimulus
GO:0005085 IEA:TAS guanyl-nucleotide exchange factor activity
GO:0005509 IEA calcium ion binding
GO:0005622 IEA intracellular
GO:0005783 IEA endoplasmic reticulum
GO:0005794 IEA Golgi apparatus
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0007165 TAS signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0007265 IEA Ras protein signal transduction
GO:0007596 TAS blood coagulation
GO:0008289 TAS lipid binding
GO:0014066 IEA regulation of phosphatidylinositol 3-kinase signaling
GO:0016020 TAS membrane
GO:0030154 IEA cell differentiation
GO:0030168 TAS platelet activation
GO:0032252 IEA secretory granule localization
GO:0032856 IEA activation of Ras GTPase activity
GO:0032862 IEA activation of Rho GTPase activity
GO:0035556 IEA intracellular signal transduction
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0042629 IEA mast cell granule
GO:0043303 IEA mast cell degranulation
GO:0043547 IEA positive regulation of GTPase activity
GO:0045087 TAS innate immune response
GO:0047496 IEA vesicle transport along microtubule
GO:0051056 IEA regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000027347 Rasgrp1 RAS guanyl releasing protein 1 protein_coding Mus_musculus

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