C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: copper chaperone for superoxide dismutase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000173992 CCS 9606 + 11:66592821-66606019 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000310190 CCS-009 66593241-66605919 protein_coding
  ENST00000525435 CCS-003 66600435-66606017 retained_intron
  ENST00000526058 CCS-004 66593204-66599611 retained_intron
  ENST00000526066 CCS-008 66593190-66599803 retained_intron
  ENST00000530384 CCS-002 66593153-66605912 retained_intron
  ENST00000530961 CCS-005 66593201-66605998 nonsense_mediated_decay
  ENST00000531990 CCS-006 66593233-66605298 retained_intron
  ENST00000533244 CCS-001 66592821-66606019 protein_coding
  ENST00000534763 CCS-007 66600034-66605780 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000310190ENST00000525435ENST00000526066ENST00000530384ENST00000530961ENST00000531990ENST00000533244ENST00000534763
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000310190 12.867±0.00 11.189±0.00 2.211±0.00 7.434±4.92 11.932±0.00 10.182±9.28 2.461±1.60 13.392±5.43 13.523±11.68 5.206±2.43 4.101±3.28 10.540±8.07 12.552±3.60 17.202±0.00
ENST00000525435 N/A N/A N/A 0.942±0.00 0.518±0.00 N/A 1.367±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000526066 N/A N/A N/A N/A N/A N/A 0.314±0.00 N/A 0.882±0.00 0.878±0.00 N/A N/A N/A N/A
ENST00000530384 N/A 3.552±0.00 N/A N/A 1.021±0.00 2.341±0.00 1.185±0.00 N/A 1.492±0.00 2.308±0.00 0.947±0.00 9.101±3.29 N/A 11.429±0.00
ENST00000530961 N/A 5.311±0.00 0.324±0.00 N/A N/A N/A N/A N/A N/A 2.502±0.00 N/A 7.453±0.90 N/A 12.586±0.00
ENST00000531990 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.713±0.00 3.589±0.00 N/A N/A
ENST00000533244 11.974±0.00 9.843±0.00 0.318±0.00 7.418±0.00 9.020±8.44 13.709±0.00 0.192±0.00 10.646±0.00 8.656±0.00 4.508±0.00 3.306±0.00 16.731±16.35 13.544±1.70 17.895±0.00
ENST00000534763 N/A N/A N/A N/A N/A 1.131±0.00 N/A 5.614±0.00 N/A N/A N/A 2.538±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003YI CIL_0003YI_0002 CGP 11:66592821-66627347

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004784 IEA superoxide dismutase activity
GO:0005375 TAS copper ion transmembrane transporter activity
GO:0005507 IBA copper ion binding
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006801 IEA superoxide metabolic process
GO:0008270 IBA zinc ion binding
GO:0015035 TAS protein disulfide oxidoreductase activity
GO:0015680 TAS intracellular copper ion transport
GO:0019430 IEA removal of superoxide radicals
GO:0030001 IEA metal ion transport
GO:0035434 TAS copper ion transmembrane transport
GO:0046872 IEA metal ion binding
GO:0051353 IEA positive regulation of oxidoreductase activity
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000092003 ccs copper chaperone for superoxide dismutase protein_coding Danio_rerio
ENSMUSG00000034108 Ccs copper chaperone for superoxide dismutase protein_coding Mus_musculus

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