C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DENN/MADD domain containing 4A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000174485 DENND4A 9606 - 15:65658046-65792293 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000431932 DENND4A-003 65661777-65792124 protein_coding
  ENST00000443035 DENND4A-001 65659123-65792124 protein_coding
  ENST00000561863 DENND4A-009 65658046-65661929 protein_coding
  ENST00000562028 DENND4A-006 65696316-65701801 retained_intron
  ENST00000562540 DENND4A-008 65661821-65664956 retained_intron
  ENST00000564674 DENND4A-005 65691458-65792293 protein_coding
  ENST00000567323 DENND4A-007 65680635-65690538 processed_transcript
  ENST00000568515 DENND4A-004 65715075-65792207 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000431932ENST00000443035ENST00000564674ENST00000568515
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000431932 1.962±0.00 1.635±0.00 1.399±0.00 3.330±1.56 1.251±0.00 2.769±0.00 0.893±0.23 1.451±0.14 2.060±0.71 5.317±3.13 0.693±0.00 1.947±0.99 0.861±0.14 1.889±0.07
ENST00000443035 1.649±0.00 1.582±0.00 0.895±0.00 1.901±0.31 0.984±0.00 1.685±0.00 0.466±0.12 1.563±0.37 1.459±0.16 2.887±0.48 1.391±0.88 1.265±0.47 N/A 2.389±1.06
ENST00000564674 N/A N/A 1.779±0.00 N/A N/A 2.353±0.00 N/A 1.769±0.00 N/A N/A N/A N/A N/A N/A
ENST00000568515 N/A N/A N/A 7.339±0.00 N/A N/A 1.590±0.00 N/A 3.888±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006HP CIL_0006HP_0002 CGP 15:65578753-65660995
CIL_0004VF CIL_0004VF_0002 CGP 15:65611366-65792293

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003677 NAS DNA binding
GO:0005634 IEA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0017112 IDA Rab guanyl-nucleotide exchange factor activity
GO:0032851 IDA positive regulation of Rab GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062721 dennd4a DENN/MADD domain containing 4A protein_coding Danio_rerio
ENSMUSG00000053641 Dennd4a DENN/MADD domain containing 4A protein_coding Mus_musculus

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