| Transcript ID | Lung | Ovary |
|---|---|---|
| ENST00000399849 | 24.286±0.00 | 65.921±27.22 |
C-It-Loci: A knowledge database for tissue-enriched loci.
Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main
Gene Info | |||||
|---|---|---|---|---|---|
| Description: | hypermethylated in cancer 1 | ||||
| Gene Accession | Gene Name | Tax ID | Strand | Position | Gene Biotype |
ENSG00000177374  |
HIC1 | 9606 | + |
17:2054154-2063241  |
protein_coding |
| Transcript Accession | Transcript Name | Position | Transcript Biotype | ||
| ENST00000322941 |
HIC1-005 | 2056310-2059686 | protein_coding | ||
| ENST00000399849 |
HIC1-201 | 2055099-2059686 | protein_coding | ||
| ENST00000571875 |
HIC1-002 | 2054215-2056889 | protein_coding | ||
| ENST00000571990 |
HIC1-003 | 2054215-2056979 | protein_coding | ||
| ENST00000574370 |
HIC1-001 | 2054154-2056719 | protein_coding | ||
| ENST00000576444 |
HIC1-004 | 2056219-2056943 | protein_coding | ||
| ENST00000619757 |
HIC1-006 | 2055099-2063241 | protein_coding | ||
Expression Patterns
|
Conserved Regions | |||
|---|---|---|---|
| Region ID | Sub-Region | Region Type | Position |
| CIL_00093G | CIL_00093G_0001 | VISTA | 17:1876478-2477942 |
| CIL_0007RP | CIL_0007RP_0001 | VISTA | 17:1878704-2480995 |
| CIL_0007KQ | CIL_0007KQ_0001 | UCNEbase | 17:1996571-2212289 |
Gene Ontology |
||
|---|---|---|
| GO ID | Evidence Type | GO Description |
| GO:0000122 | IEA:ISS | negative regulation of transcription from RNA polymerase II promoter |
| GO:0000785 | ISS | chromatin |
| GO:0003700 | IEA:IDA | sequence-specific DNA binding transcription factor activity |
| GO:0005515 | IPI:IEA | protein binding |
| GO:0005634 | IDA | nucleus |
| GO:0005737 | IDA | cytoplasm |
| GO:0006351 | IEA | transcription, DNA-templated |
| GO:0006355 | TAS | regulation of transcription, DNA-templated |
| GO:0007275 | IEA | multicellular organismal development |
| GO:0008630 | IEA:IDA | intrinsic apoptotic signaling pathway in response to DNA damage |
| GO:0016055 | IEA | Wnt signaling pathway |
| GO:0030178 | IDA | negative regulation of Wnt signaling pathway |
| GO:0042826 | IDA | histone deacetylase binding |
| GO:0043517 | ISS | positive regulation of DNA damage response, signal transduction by p53 class mediator |
| GO:0043565 | IDA | sequence-specific DNA binding |
| GO:0046872 | IEA | metal ion binding |
Homologs | |||||
| ENSEMBL Accession | Gene Name | Description | Biotype | Species | |
|
ENSDARG00000055493
|
hic1 | hypermethylated in cancer 1 | protein_coding | Danio_rerio | |
|
ENSMUSG00000043099
|
Hic1 | hypermethylated in cancer 1 | protein_coding | Mus_musculus | |
