C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hypermethylated in cancer 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000043099 Hic1 10090 - 11:75164565-75169519 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000055619 Hic1-001 75164565-75169519 protein_coding
  ENSMUST00000131720 Hic1-002 75167153-75168146 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000055619
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000055619 9.216±4.44 1.974±0.54 3.072±0.22 1.071±0.71 4.123±0.92 4.925±1.59 1.313±0.36 0.876±0.26 0.408±0.14 3.495±1.36 1.167±0.88 12.779±4.61 15.040±8.83 0.405±0.11

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007RP CIL_0007RP_0002 VISTA 11:74746156-75348336
CIL_00093G CIL_00093G_0002 VISTA 11:74749027-75350435
CIL_0007KQ CIL_0007KQ_0002 UCNEbase 11:75016990-75215448

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0008630 IEA intrinsic apoptotic signaling pathway in response to DNA damage
GO:0030178 IEA negative regulation of Wnt signaling pathway
GO:0042826 IEA histone deacetylase binding
GO:0043565 IEA sequence-specific DNA binding
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000055493 hic1 hypermethylated in cancer 1 protein_coding Danio_rerio
ENSG00000177374 HIC1 hypermethylated in cancer 1 protein_coding Homo_sapiens

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