C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: mitochondrial elongation factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177427 MIEF2 9606 + 17:18260534-18266552 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000323019 MIEF2-001 18260534-18266552 protein_coding
  ENST00000395703 MIEF2-004 18260604-18263515 protein_coding
  ENST00000395704 MIEF2-002 18260597-18266204 protein_coding
  ENST00000395706 MIEF2-003 18261110-18265781 protein_coding
  ENST00000577216 MIEF2-007 18260616-18264127 processed_transcript
  ENST00000578174 MIEF2-005 18260597-18263546 protein_coding
  ENST00000578621 MIEF2-006 18260645-18263802 protein_coding
  ENST00000579341 MIEF2-011 18260661-18263881 protein_coding
  ENST00000583745 MIEF2-008 18260662-18263181 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000323019ENST00000395704ENST00000395706ENST00000578174ENST00000578621ENST00000579341
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000323019 N/A 0.583±0.00 N/A 0.467±0.00 N/A N/A 0.779±0.00 1.160±0.00 0.362±0.00 N/A 1.059±0.26 1.640±0.34 1.669±0.13 0.725±0.08
ENST00000395704 0.510±0.00 0.712±0.00 0.703±0.00 0.564±0.00 0.688±0.00 0.271±0.08 0.304±0.00 N/A N/A 0.150±0.00 N/A N/A 0.553±0.00 N/A
ENST00000395706 1.690±0.00 0.943±0.00 0.351±0.00 4.467±0.00 1.397±1.11 1.176±0.21 1.632±1.24 3.510±2.97 0.669±0.07 1.445±0.44 2.355±1.56 3.434±2.57 2.915±0.83 1.723±0.56
ENST00000578174 N/A N/A N/A N/A N/A N/A 1.021±0.00 N/A 1.482±0.00 N/A N/A N/A N/A N/A
ENST00000578621 N/A N/A N/A 2.482±0.00 1.701±0.00 2.282±0.00 N/A N/A N/A N/A 3.574±0.00 N/A N/A N/A
ENST00000579341 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.345±0.97 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000E4 CIL_0000E4_0001 CGP 17:18244836-18266552
CIL_0005K3 CIL_0005K3_0001 CGP 17:18260534-18315007

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005739 IDA mitochondrion
GO:0005741 IDA mitochondrial outer membrane
GO:0007005 IDA mitochondrion organization
GO:0016021 IEA integral component of membrane
GO:0032464 IDA positive regulation of protein homooligomerization
GO:0090141 IDA positive regulation of mitochondrial fission
GO:0090314 IDA positive regulation of protein targeting to membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000002377 mief2 mitochondrial elongation factor 2 protein_coding Danio_rerio
ENSMUSG00000018599 Mief2 mitochondrial elongation factor 2 protein_coding Mus_musculus

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