Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	mitochondrial elongation factor 2
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSMUSG00000018599	Mief2	10090	+	11:60728398-60732951	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENSMUST00000018743		Mief2-001	60728398-60732951	protein_coding
	ENSMUST00000146159		Mief2-002	60728445-60730663	processed_transcript
	ENSMUST00000154890		Mief2-003	60728443-60730996	retained_intron

Expression Patterns

Transcript ID	Adipose	Adrenal	Bladder	Brain	Breast	Colon	Heart	Kidney	Liver	Lung	Muscle	Ovary	Placenta	Testis
ENSMUST00000018743	6.443±1.78	16.402±1.39	5.365±0.26	3.803±1.93	8.395±3.02	5.140±0.93	10.561±0.85	5.196±0.76	4.367±3.38	7.004±0.86	29.267±3.85	7.305±3.22	3.125±1.18	1.712±0.79
ENSMUST00000154890	N/A	11.784±0.55	3.587±0.00	3.516±0.51	5.454±0.01	4.085±0.64	6.585±0.00	N/A	2.044±2.04	N/A	N/A	5.960±0.97	N/A	1.161±0.00

Conserved Regions
Region ID	Sub-Region	Region Type	Position
CIL_0000E4	CIL_0000E4_0002	CGP	11:60714123-60732951
CIL_0005K3	CIL_0005K3_0002	CGP	11:60728398-60777365

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0003674	ND	molecular_function
GO:0005515	IEA	protein binding
GO:0005739	ISS	mitochondrion
GO:0005741	ISS	mitochondrial outer membrane
GO:0007005	ISS	mitochondrion organization
GO:0016021	IEA	integral component of membrane
GO:0032464	ISS	positive regulation of protein homooligomerization
GO:0090141	ISS	positive regulation of mitochondrial fission
GO:0090314	ISS	positive regulation of protein targeting to membrane

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000002377	mief2	mitochondrial elongation factor 2	protein_coding	Danio_rerio
ENSG00000177427	MIEF2	mitochondrial elongation factor 2	protein_coding	Homo_sapiens

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