C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: patatin-like phospholipase domain containing 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000177666 PNPLA2 9606 + 11:818902-825573 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000336615 PNPLA2-001 818902-825573 protein_coding
  ENST00000525250 PNPLA2-002 820835-825219 retained_intron
  ENST00000526083 PNPLA2-006 823648-824437 retained_intron
  ENST00000529255 PNPLA2-003 823543-825218 retained_intron
  ENST00000531923 PNPLA2-007 822016-823572 retained_intron
  ENST00000534561 PNPLA2-005 821774-822258 retained_intron
  ENST00000617551 PNPLA2-201 820835-825219 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000336615ENST00000529255
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000336615 307.125±0.00 2.199±0.00 8.328±6.94 222.592±218.45 23.615±17.68 46.776±44.17 32.478±0.00 4.615±0.00 3.521±0.00 7.728±0.00 23.082±20.00 35.663±0.28 28.220±5.28
ENST00000529255 296.347±0.00 N/A N/A 458.293±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003EM CIL_0003EM_0001 CGP 11:809647-825573
CIL_0003EN CIL_0003EN_0001 CGP 11:818902-831991

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004806 ISS triglyceride lipase activity
GO:0005515 IEA protein binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0005811 IDA lipid particle
GO:0005829 IEA cytosol
GO:0005886 IEA plasma membrane
GO:0006629 IEA lipid metabolic process
GO:0006644 TAS phospholipid metabolic process
GO:0008152 IEA metabolic process
GO:0010891 IDA negative regulation of sequestering of triglyceride
GO:0010898 IDA positive regulation of triglyceride catabolic process
GO:0016021 IEA integral component of membrane
GO:0019433 IEA triglyceride catabolic process
GO:0019915 IEA lipid storage
GO:0034389 IEA lipid particle organization
GO:0036155 TAS acylglycerol acyl-chain remodeling
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0046474 TAS glycerophospholipid biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073955 PNPLA2 patatin-like phospholipase domain containing 2 protein_coding Danio_rerio
ENSMUSG00000025509 Pnpla2 patatin-like phospholipase domain containing 2 protein_coding Mus_musculus

Loading