C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: patatin-like phospholipase domain containing 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000025509 Pnpla2 10090 + 7:141455198-141460743 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000026583 Pnpla2-002 141455206-141460092 nonsense_mediated_decay
  ENSMUST00000064151 Pnpla2-005 141455207-141460094 protein_coding
  ENSMUST00000164016 Pnpla2-001 141455198-141460743 protein_coding
  ENSMUST00000164924 Pnpla2-003 141455229-141460103 nonsense_mediated_decay
  ENSMUST00000165487 Pnpla2-007 141455607-141458151 protein_coding
  ENSMUST00000169665 Pnpla2-006 141455219-141458938 protein_coding
  ENSMUST00000169723 Pnpla2-008 141457018-141458686 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000026583ENSMUST00000064151ENSMUST00000164016ENSMUST00000164924ENSMUST00000165487ENSMUST00000169665ENSMUST00000169723
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000026583 388.518±205.12 99.277±25.75 28.513±1.17 1.994±0.25 194.235±93.98 19.122±4.55 82.251±19.69 47.639±3.49 3.896±1.83 20.673±1.17 50.252±2.64 34.206±30.74 6.759±4.56 43.808±20.33
ENSMUST00000064151 449.234±234.33 379.087±108.42 25.946±0.42 3.762±0.69 606.689±108.01 65.009±8.33 112.153±39.30 80.373±7.60 12.854±8.32 75.993±25.12 22.209±3.63 66.129±5.95 6.208±3.29 91.411±8.16
ENSMUST00000164016 66.328±1.01 59.387±23.80 N/A N/A 108.075±5.14 10.788±0.22 16.707±0.00 N/A 0.899±0.26 31.804±9.06 N/A 10.816±3.39 N/A N/A
ENSMUST00000164924 N/A N/A N/A 1.212±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 0.676±0.00 N/A
ENSMUST00000165487 N/A N/A N/A N/A 804.421±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENSMUST00000169665 N/A N/A N/A 1.795±0.00 N/A N/A N/A N/A N/A N/A 27.719±4.68 9.408±0.00 4.431±2.67 10.876±0.00
ENSMUST00000169723 N/A N/A N/A N/A 198.217±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003EM CIL_0003EM_0002 CGP 7:141447370-141460743
CIL_0003EN CIL_0003EN_0002 CGP 7:141455198-141466613

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004806 IDA triglyceride lipase activity
GO:0005515 IPI protein binding
GO:0005811 IDA lipid particle
GO:0005829 IDA cytosol
GO:0005886 IEA plasma membrane
GO:0010891 IDA negative regulation of sequestering of triglyceride
GO:0010898 IDA positive regulation of triglyceride catabolic process
GO:0016021 IEA integral component of membrane
GO:0019433 IMP triglyceride catabolic process
GO:0019915 IMP lipid storage
GO:0034389 IMP lipid particle organization
GO:0043231 IEA intracellular membrane-bounded organelle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000073955 PNPLA2 patatin-like phospholipase domain containing 2 protein_coding Danio_rerio
ENSG00000177666 PNPLA2 patatin-like phospholipase domain containing 2 protein_coding Homo_sapiens

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