C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: myeloid leukemia factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000178053 MLF1 9606 + 3:158571163-158607252 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355893 MLF1-001 158571163-158606460 protein_coding
  ENST00000359117 MLF1-004 158571184-158606456 protein_coding
  ENST00000392822 MLF1-201 158582835-158606459 protein_coding
  ENST00000466246 MLF1-014 158571261-158600173 protein_coding
  ENST00000469452 MLF1-006 158571195-158605399 protein_coding
  ENST00000471745 MLF1-002 158571194-158605392 protein_coding
  ENST00000477042 MLF1-013 158571194-158600159 protein_coding
  ENST00000478894 MLF1-008 158571254-158605401 protein_coding
  ENST00000482628 MLF1-007 158571210-158605218 protein_coding
  ENST00000484955 MLF1-005 158571173-158605397 protein_coding
  ENST00000487838 MLF1-010 158571261-158598160 nonsense_mediated_decay
  ENST00000491767 MLF1-015 158571163-158605192 protein_coding
  ENST00000495452 MLF1-012 158571194-158600175 nonsense_mediated_decay
  ENST00000497004 MLF1-003 158571194-158607252 processed_transcript
  ENST00000498592 MLF1-009 158571191-158602939 protein_coding
  ENST00000618075 MLF1-202 158571164-158606459 protein_coding
  ENST00000619577 MLF1-203 158571164-158606459 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355893ENST00000359117ENST00000392822ENST00000466246ENST00000469452ENST00000471745ENST00000477042ENST00000482628ENST00000484955ENST00000491767ENST00000495452ENST00000498592ENST00000619577
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355893 N/A 0.244±0.00 0.929±0.00 2.081±0.00 1.236±0.00 0.665±0.00 3.994±0.00 1.008±0.00 1.527±0.00 1.757±0.41 1.111±0.78 1.360±0.30 0.178±0.06 N/A
ENST00000359117 0.567±0.00 N/A N/A 2.409±0.00 0.911±0.13 0.793±0.00 7.324±0.00 0.525±0.00 0.095±0.00 1.002±0.00 N/A 0.690±0.58 0.145±0.00 N/A
ENST00000392822 N/A N/A N/A N/A N/A N/A N/A 0.076±0.00 N/A N/A N/A N/A 0.146±0.00 N/A
ENST00000466246 N/A N/A N/A N/A N/A N/A 10.757±0.00 N/A N/A N/A 9.715±0.00 N/A 0.630±0.00 137.169±0.00
ENST00000469452 N/A 0.649±0.00 N/A N/A N/A N/A N/A 0.108±0.00 N/A N/A N/A N/A N/A N/A
ENST00000471745 N/A N/A N/A N/A 1.119±0.00 N/A 19.747±17.10 N/A N/A N/A 2.583±0.11 N/A N/A N/A
ENST00000477042 N/A N/A N/A N/A N/A N/A 4.667±0.00 N/A N/A 2.758±0.00 4.702±0.00 0.390±0.00 N/A 75.976±0.00
ENST00000482628 N/A 0.734±0.00 N/A N/A N/A N/A N/A N/A N/A 3.458±0.00 1.416±0.00 N/A N/A N/A
ENST00000484955 0.854±0.00 0.343±0.00 N/A 3.774±0.00 2.759±0.00 5.837±0.00 N/A 2.889±0.00 0.077±0.00 6.426±0.00 N/A 4.224±2.98 0.388±0.25 76.491±33.43
ENST00000491767 1.797±0.00 N/A N/A 5.643±0.00 1.947±0.00 N/A N/A N/A N/A N/A N/A 0.143±0.00 0.385±0.16 154.076±0.00
ENST00000495452 N/A N/A N/A N/A 1.808±0.00 0.766±0.00 N/A N/A N/A N/A N/A 0.116±0.00 N/A N/A
ENST00000498592 N/A N/A N/A N/A N/A N/A N/A 2.297±0.00 0.909±0.00 N/A N/A N/A N/A N/A
ENST00000619577 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.408±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BN CIL_0008BN_0001 VISTA 3:157971822-158572677
CIL_00086V CIL_00086V_0001 VISTA 3:157991733-158593047
CIL_0008BM CIL_0008BM_0001 VISTA 3:158007957-158609595
CIL_0008KO CIL_0008KO_0001 VISTA 3:158067861-158669043
CIL_000808 CIL_000808_0001 VISTA 3:158183764-158784540
CIL_000815 CIL_000815_0001 VISTA 3:158228062-158828791
CIL_000937 CIL_000937_0001 VISTA 3:158468467-159075583
CIL_0004JV CIL_0004JV_0002 CGP 3:158571163-158692575

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002318 ISS myeloid progenitor cell differentiation
GO:0003677 ISS DNA binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0006351 ISS transcription, DNA-templated
GO:0007050 IDA cell cycle arrest
GO:0019904 IDA protein domain specific binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000077301 mlf1 myeloid leukemia factor 1 protein_coding Danio_rerio
ENSMUSG00000048416 Mlf1 myeloid leukemia factor 1 protein_coding Mus_musculus

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