C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000178394 HTR1A 9606 - 5:63960356-63962507 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000323865 HTR1A-001 63960356-63962133 protein_coding
  ENST00000506598 HTR1A-003 63961595-63962507 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainKidneyOvaryENST00000323865ENST00000506598
Transcript ID Brain Kidney Ovary
ENST00000323865 0.647±0.00 N/A 0.110±0.06
ENST00000506598 N/A 0.061±0.00 0.080±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZN CIL_0007ZN_0001 VISTA 5:63585672-64187029

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001662 ISS behavioral fear response
GO:0004930 IEA G-protein coupled receptor activity
GO:0004993 IMP serotonin receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IEA:IDA integral component of plasma membrane
GO:0007186 IMP:IEA G-protein coupled receptor signaling pathway
GO:0007198 IDA adenylate cyclase-inhibiting serotonin receptor signaling pathway
GO:0007210 ISS serotonin receptor signaling pathway
GO:0008283 IEA cell proliferation
GO:0008284 TAS positive regulation of cell proliferation
GO:0014062 ISS regulation of serotonin secretion
GO:0016021 IEA integral component of membrane
GO:0035640 ISS exploration behavior
GO:0042053 ISS regulation of dopamine metabolic process
GO:0042310 IEA vasoconstriction
GO:0042428 ISS serotonin metabolic process
GO:0046883 IEA regulation of hormone secretion
GO:0050795 IEA regulation of behavior

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000093745 htr1aa 5-hydroxytryptamine (serotonin) receptor 1A a protein_coding Danio_rerio
ENSMUSG00000021721 Htr1a 5-hydroxytryptamine (serotonin) receptor 1A protein_coding Mus_musculus

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