C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000323865 HTR1A-001 ENSG00000178394 9606 - 5:63960356-63962133 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainOvaryENST00000323865
Transcript ID Brain Ovary
ENST00000323865 0.647±0.00 0.110±0.06

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007ZN CIL_0007ZN_0001 VISTA 5:63585672-64187029

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001662 ISS behavioral fear response
GO:0004930 IEA G-protein coupled receptor activity
GO:0004993 IMP serotonin receptor activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0005887 IEA:IDA integral component of plasma membrane
GO:0007186 IMP:IEA G-protein coupled receptor signaling pathway
GO:0007198 IDA adenylate cyclase-inhibiting serotonin receptor signaling pathway
GO:0007210 ISS serotonin receptor signaling pathway
GO:0008283 IEA cell proliferation
GO:0008284 TAS positive regulation of cell proliferation
GO:0014062 ISS regulation of serotonin secretion
GO:0016021 IEA integral component of membrane
GO:0035640 ISS exploration behavior
GO:0042053 ISS regulation of dopamine metabolic process
GO:0042310 IEA vasoconstriction
GO:0042428 ISS serotonin metabolic process
GO:0046883 IEA regulation of hormone secretion
GO:0050795 IEA regulation of behavior

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000022235 Htr1a-201 protein_coding Mus_musculus 0 1500

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