C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: 5-hydroxytryptamine (serotonin) receptor 1A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021721 Htr1a 10090 + 13:105443693-105448133 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000022235 Htr1a-201 105443693-105448133 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainLiverTestisENSMUST00000022235
Transcript ID Bladder Brain Liver Testis
ENSMUST00000022235 0.002±0.00 0.922±0.33 0.003±0.00 0.020±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005HF CIL_0005HF_0002 CGP 13:105149352-105448133
CIL_0007ZN CIL_0007ZN_0002 VISTA 13:105237275-105839272
CIL_0007EY CIL_0007EY_0002 CGP 13:105443693-106936958

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001662 IMP behavioral fear response
GO:0004993 IDA serotonin receptor activity
GO:0005515 IEA protein binding
GO:0005887 ISS integral component of plasma membrane
GO:0007198 ISS adenylate cyclase-inhibiting serotonin receptor signaling pathway
GO:0007210 IMP serotonin receptor signaling pathway
GO:0008283 IEA cell proliferation
GO:0014062 IMP regulation of serotonin secretion
GO:0035640 IMP exploration behavior
GO:0042053 IMP regulation of dopamine metabolic process
GO:0042310 IEA vasoconstriction
GO:0042428 IMP serotonin metabolic process
GO:0046883 IEA regulation of hormone secretion
GO:0050795 IEA regulation of behavior

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000093745 htr1aa 5-hydroxytryptamine (serotonin) receptor 1A a protein_coding Danio_rerio
ENSG00000178394 HTR1A 5-hydroxytryptamine (serotonin) receptor 1A, G protein-coupled protein_coding Homo_sapiens

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