C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dihydrofolate reductase-like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000178700 DHFRL1 9606 - 3:94047836-94063389 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000314636 DHFRL1-002 94057922-94062987 protein_coding
  ENST00000394221 DHFRL1-001 94057924-94063223 protein_coding
  ENST00000461173 DHFRL1-003 94058725-94062899 nonsense_mediated_decay
  ENST00000481631 DHFRL1-005 94047836-94062841 processed_transcript
  ENST00000496983 DHFRL1-004 94061169-94063389 protein_coding
  ENST00000619045 DHFRL1-201 94058754-94062899 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000314636ENST00000394221ENST00000461173ENST00000619045
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000314636 1.021±0.00 1.167±0.00 0.855±0.00 1.647±0.80 0.872±0.07 0.708±0.00 0.665±0.00 1.703±0.48 1.080±0.00 0.406±0.00 0.320±0.00 1.691±0.85 1.302±0.50 1.079±0.32
ENST00000394221 N/A 0.738±0.00 N/A N/A 0.466±0.00 0.588±0.07 N/A N/A N/A N/A N/A N/A N/A 0.607±0.00
ENST00000461173 N/A N/A N/A N/A N/A 1.966±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000619045 N/A N/A N/A N/A N/A N/A N/A N/A 2.730±0.00 1.941±0.00 0.198±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003B0 CIL_0003B0_0001 CGP 3:93980139-94055668
CIL_0007VB CIL_0007VB_0001 VISTA 3:94032174-94634985

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003729 IDA mRNA binding
GO:0004146 IEA:IMP dihydrofolate reductase activity
GO:0005739 IDA mitochondrion
GO:0005743 IMP mitochondrial inner membrane
GO:0005759 IMP mitochondrial matrix
GO:0006545 IEA glycine biosynthetic process
GO:0006730 IEA one-carbon metabolic process
GO:0009165 IEA nucleotide biosynthetic process
GO:0046105 IDA thymidine biosynthetic process
GO:0046653 IDA tetrahydrofolate metabolic process
GO:0046654 IEA tetrahydrofolate biosynthetic process
GO:0050661 IEA NADP binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004251 dhfr dihydrofolate reductase protein_coding Danio_rerio
ENSMUSG00000021707 Dhfr dihydrofolate reductase protein_coding Mus_musculus

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