C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dihydrofolate reductase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSDARG00000004251 dhfr 7955 + 5:27782862-27791037 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSDART00000010041 dhfr-001 27782862-27791037 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainHeartKidneyLiverMuscleENSDART00000010041
Transcript ID Brain Heart Kidney Liver Muscle
ENSDART00000010041 1.883±0.29 2.573±1.02 14.719±2.88 0.384±0.00 0.869±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002ZB CIL_0002ZB_0001 CGP 5:27782862-27804470

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001947 IMP heart looping
GO:0003007 IGI heart morphogenesis
GO:0004146 IEA dihydrofolate reductase activity
GO:0006545 IEA glycine biosynthetic process
GO:0009165 IEA nucleotide biosynthetic process
GO:0016491 IEA oxidoreductase activity
GO:0046655 IMP folic acid metabolic process
GO:0048598 IMP embryonic morphogenesis
GO:0050661 IEA NADP binding
GO:0055114 IEA oxidation-reduction process
GO:0060047 IMP heart contraction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000178700 DHFRL1 dihydrofolate reductase-like 1 protein_coding Homo_sapiens
ENSG00000228716 DHFR dihydrofolate reductase protein_coding Homo_sapiens
ENSMUSG00000021707 Dhfr dihydrofolate reductase protein_coding Mus_musculus

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