C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth arrest-specific 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000180447 GAS1 9606 - 9:86944363-86947189 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000298743 GAS1-001 86944363-86947189 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000298743
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000298743 11.919±0.00 7.334±0.00 0.977±0.00 1.445±0.33 11.292±6.61 7.586±4.81 4.531±2.65 5.898±5.75 1.205±0.32 2.831±0.64 4.240±0.69 18.210±16.08 33.283±12.94 8.943±7.91

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YF CIL_0000YF_0001 CGP 9:86287733-86947189
CIL_0007Z4 CIL_0007Z4_0001 VISTA 9:86601211-87204420
CIL_0007VC CIL_0007VC_0001 VISTA 9:86733435-87336683

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002053 IEA positive regulation of mesenchymal cell proliferation
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0007050 IEA cell cycle arrest
GO:0007411 IEA axon guidance
GO:0008284 IEA positive regulation of cell proliferation
GO:0008589 ISS regulation of smoothened signaling pathway
GO:0009953 IEA dorsal/ventral pattern formation
GO:0010955 IMP negative regulation of protein processing
GO:0012501 IEA programmed cell death
GO:0016020 IEA membrane
GO:0016021 NAS integral component of membrane
GO:0021587 IEA cerebellum morphogenesis
GO:0021904 IEA dorsal/ventral neural tube patterning
GO:0030308 IEA negative regulation of cell growth
GO:0035924 IEP cellular response to vascular endothelial growth factor stimulus
GO:0042473 IEA outer ear morphogenesis
GO:0042474 IEA middle ear morphogenesis
GO:0042476 IEA odontogenesis
GO:0042733 IEA embryonic digit morphogenesis
GO:0042981 ISS regulation of apoptotic process
GO:0043010 IEA camera-type eye development
GO:0043066 IEA negative regulation of apoptotic process
GO:0045165 ISS cell fate commitment
GO:0045879 IEA negative regulation of smoothened signaling pathway
GO:0045880 IEA positive regulation of smoothened signaling pathway
GO:0045930 IGI negative regulation of mitotic cell cycle
GO:0046658 ISS anchored component of plasma membrane
GO:0048589 ISS developmental growth
GO:0048592 IEA eye morphogenesis
GO:0048598 IEA embryonic morphogenesis
GO:0048701 IEA embryonic cranial skeleton morphogenesis
GO:0048706 IEA embryonic skeletal system development
GO:0050679 IEA positive regulation of epithelial cell proliferation
GO:0050680 IEA negative regulation of epithelial cell proliferation
GO:0060021 IEA palate development
GO:0060628 IMP regulation of ER to Golgi vesicle-mediated transport
GO:2001240 IEA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000067984 gas1b growth arrest-specific 1b protein_coding Danio_rerio
ENSDARG00000077298 gas1a growth arrest-specific 1a protein_coding Danio_rerio
ENSMUSG00000052957 Gas1 growth arrest specific 1 protein_coding Mus_musculus

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