C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: growth arrest specific 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000052957 Gas1 10090 - 13:60174405-60177365 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000065086 Gas1-001 60174405-60177365 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000065086
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000065086 83.138±53.83 55.966±9.56 78.416±18.36 11.726±8.09 28.615±15.38 32.987±3.29 8.530±1.34 16.863±3.79 5.675±4.02 24.932±5.66 4.238±0.74 133.424±62.18 5.236±6.04 1.670±0.96

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000YF CIL_0000YF_0002 CGP 13:59771879-60177365
CIL_0007Z4 CIL_0007Z4_0002 VISTA 13:59845681-60449199
CIL_0007VC CIL_0007VC_0002 VISTA 13:59967007-60570395

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002053 IMP positive regulation of mesenchymal cell proliferation
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0007050 TAS cell cycle arrest
GO:0007411 IMP axon guidance
GO:0008284 IMP positive regulation of cell proliferation
GO:0008589 IMP regulation of smoothened signaling pathway
GO:0009953 IMP dorsal/ventral pattern formation
GO:0010955 ISS negative regulation of protein processing
GO:0012501 IDA programmed cell death
GO:0016020 IDA membrane
GO:0021587 IMP cerebellum morphogenesis
GO:0021904 IMP dorsal/ventral neural tube patterning
GO:0030308 IDA negative regulation of cell growth
GO:0035924 IEA cellular response to vascular endothelial growth factor stimulus
GO:0042473 IMP outer ear morphogenesis
GO:0042474 IMP middle ear morphogenesis
GO:0042476 IMP odontogenesis
GO:0042733 IGI embryonic digit morphogenesis
GO:0043010 IMP camera-type eye development
GO:0043066 IMP negative regulation of apoptotic process
GO:0045165 IMP cell fate commitment
GO:0045879 IDA negative regulation of smoothened signaling pathway
GO:0045880 IDA positive regulation of smoothened signaling pathway
GO:0045930 ISS negative regulation of mitotic cell cycle
GO:0046658 IDA anchored component of plasma membrane
GO:0048589 IMP developmental growth
GO:0048592 IMP eye morphogenesis
GO:0048598 IGI embryonic morphogenesis
GO:0048701 IGI embryonic cranial skeleton morphogenesis
GO:0048706 IGI embryonic skeletal system development
GO:0050679 IMP positive regulation of epithelial cell proliferation
GO:0050680 IMP negative regulation of epithelial cell proliferation
GO:0060021 IMP palate development
GO:0060628 ISS regulation of ER to Golgi vesicle-mediated transport
GO:2001240 IDA negative regulation of extrinsic apoptotic signaling pathway in absence of ligand

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000067984 gas1b growth arrest-specific 1b protein_coding Danio_rerio
ENSDARG00000077298 gas1a growth arrest-specific 1a protein_coding Danio_rerio
ENSG00000180447 GAS1 growth arrest-specific 1 protein_coding Homo_sapiens

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