C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proenkephalin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000181195 PENK 9606 - 8:56436674-56446734 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000314922 PENK-002 56440954-56446030 protein_coding
  ENST00000451791 PENK-001 56441272-56446734 protein_coding
  ENST00000517415 PENK-007 56436674-56445944 protein_coding
  ENST00000518770 PENK-003 56445245-56446663 protein_coding
  ENST00000518974 PENK-010 56441759-56446572 protein_coding
  ENST00000520589 PENK-008 56436715-56438510 processed_transcript
  ENST00000521153 PENK-004 56446006-56446671 retained_intron
  ENST00000523051 PENK-005 56443518-56446641 protein_coding
  ENST00000523274 PENK-006 56441392-56445648 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartLiverLungOvaryPlacentaTestisENST00000314922ENST00000451791ENST00000523274
Transcript ID Brain Breast Colon Heart Liver Lung Ovary Placenta Testis
ENST00000314922 2.491±0.46 4.830±0.00 11.249±0.00 0.076±0.00 0.508±0.00 4.958±0.00 3.461±2.44 2.009±1.11 33.386±14.68
ENST00000451791 2.506±0.00 N/A 9.609±0.00 N/A N/A N/A 3.886±0.00 4.274±0.00 51.764±20.42
ENST00000523274 N/A N/A N/A N/A N/A N/A 2.270±1.99 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005LV CIL_0005LV_0002 CGP 8:56300010-56446734
CIL_0005LQ CIL_0005LQ_0002 CGP 8:56436674-56993844

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001515 IEA opioid peptide activity
GO:0001662 IEA behavioral fear response
GO:0001964 IEA startle response
GO:0002118 IEA aggressive behavior
GO:0005184 TAS neuropeptide hormone activity
GO:0005515 IPI protein binding
GO:0005576 IEA:TAS extracellular region
GO:0007165 TAS signal transduction
GO:0007218 IEA neuropeptide signaling pathway
GO:0007626 IEA locomotory behavior
GO:0019233 IEA sensory perception of pain

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004869 penka proenkephalin a protein_coding Danio_rerio
ENSDARG00000036045 penkb proenkephalin b protein_coding Danio_rerio
ENSMUSG00000045573 Penk preproenkephalin protein_coding Mus_musculus

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