C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: preproenkephalin
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000045573 Penk 10090 - 4:4133531-4138819 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000070375 Penk-001 4133531-4138477 protein_coding
  ENSMUST00000133567 Penk-002 4134112-4138819 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000070375ENSMUST00000133567
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000070375 2.683±1.36 N/A 4.835±0.00 0.601±0.00 6.355±4.41 1.143±0.35 0.643±0.12 0.515±0.04 0.231±0.11 0.511±0.07 2.508±0.56 37.877±20.58 2.652±4.51 50.938±15.68
ENSMUST00000133567 16.086±0.70 27.294±10.70 8.112±0.03 11.392±5.34 31.774±13.89 10.617±2.18 2.139±1.10 2.129±0.46 0.303±0.21 3.793±0.54 0.951±0.12 67.736±18.80 5.912±9.87 38.603±23.44

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005LV CIL_0005LV_0003 CGP 4:4055929-4138819
CIL_0005LQ CIL_0005LQ_0003 CGP 4:4133531-4793355

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001515 IEA opioid peptide activity
GO:0001662 IMP behavioral fear response
GO:0001964 IMP startle response
GO:0002118 IMP aggressive behavior
GO:0005515 IEA protein binding
GO:0005576 IEA extracellular region
GO:0007218 IEA neuropeptide signaling pathway
GO:0007626 IMP locomotory behavior
GO:0019233 IMP sensory perception of pain

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000004869 penka proenkephalin a protein_coding Danio_rerio
ENSDARG00000036045 penkb proenkephalin b protein_coding Danio_rerio
ENSG00000181195 PENK proenkephalin protein_coding Homo_sapiens

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