C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: LIM domain kinase 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000182541 LIMK2 9606 + 22:31212239-31280080 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331728 LIMK2-001 31212295-31280080 protein_coding
  ENST00000333611 LIMK2-004 31248402-31279734 protein_coding
  ENST00000340552 LIMK2-003 31248487-31277638 protein_coding
  ENST00000406516 LIMK2-002 31212274-31277638 protein_coding
  ENST00000425203 LIMK2-005 31248358-31258484 protein_coding
  ENST00000462625 LIMK2-006 31212239-31259046 retained_intron
  ENST00000465937 LIMK2-007 31258959-31266132 retained_intron
  ENST00000467301 LIMK2-008 31272674-31278586 processed_transcript
  ENST00000482270 LIMK2-009 31272471-31275665 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000331728ENST00000333611ENST00000340552ENST00000406516ENST00000425203ENST00000462625ENST00000482270
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000331728 8.365±0.00 12.151±0.00 0.634±0.00 3.776±3.43 4.175±2.79 2.304±0.00 0.499±0.00 4.998±4.84 1.809±0.97 20.633±0.00 0.434±0.00 13.130±3.36 15.110±6.36 8.880±2.47
ENST00000333611 N/A N/A N/A 2.443±0.00 N/A N/A 0.484±0.00 0.172±0.00 1.134±0.00 7.264±0.00 N/A 8.375±0.00 15.723±8.21 N/A
ENST00000340552 N/A N/A N/A N/A N/A N/A 0.079±0.00 N/A N/A N/A N/A N/A 6.480±0.72 N/A
ENST00000406516 N/A N/A N/A N/A 1.055±0.00 2.381±0.05 0.510±0.40 0.554±0.00 0.834±0.00 9.280±0.00 1.575±0.00 10.022±0.00 10.483±0.00 5.719±0.00
ENST00000425203 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.866±0.00 N/A N/A N/A
ENST00000462625 N/A N/A 0.941±0.00 N/A N/A N/A N/A N/A N/A 5.825±0.00 N/A 5.003±0.00 N/A N/A
ENST00000482270 N/A N/A 1.406±0.00 N/A N/A N/A N/A N/A N/A N/A 1.618±0.00 N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006EW CIL_0006EW_0002 CGP 22:31212239-31292534

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004672 IEA protein kinase activity
GO:0004674 TAS protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI:IEA protein binding
GO:0005524 IEA ATP binding
GO:0005634 TAS nucleus
GO:0005737 TAS cytoplasm
GO:0005801 IEA cis-Golgi network
GO:0006468 IEA protein phosphorylation
GO:0007283 IEA spermatogenesis
GO:0008270 IEA zinc ion binding
GO:0016310 TAS phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0042325 IEA regulation of phosphorylation
GO:0046982 IEA protein heterodimerization activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000005104 limk2 LIM domain kinase 2 protein_coding Danio_rerio
ENSMUSG00000020451 Limk2 LIM motif-containing protein kinase 2 protein_coding Mus_musculus

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