C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adaptor-related protein complex 2, alpha 2 subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000183020 AP2A2 9606 + 11:924894-1012245 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000332231 AP2A2-201 925809-1012245 protein_coding
  ENST00000448903 AP2A2-001 925881-1012239 protein_coding
  ENST00000524559 AP2A2-019 946461-977120 protein_coding
  ENST00000524952 AP2A2-014 985538-988827 retained_intron
  ENST00000525796 AP2A2-023 925872-985477 protein_coding
  ENST00000525891 AP2A2-012 996064-1009216 processed_transcript
  ENST00000526376 AP2A2-010 1003732-1007040 retained_intron
  ENST00000526401 AP2A2-025 1003667-1009774 retained_intron
  ENST00000526753 AP2A2-016 942279-972197 protein_coding
  ENST00000527024 AP2A2-020 940735-972216 protein_coding
  ENST00000527917 AP2A2-015 985384-986846 retained_intron
  ENST00000528195 AP2A2-013 925945-1000483 processed_transcript
  ENST00000528815 AP2A2-002 925900-1010919 nonsense_mediated_decay
  ENST00000528816 AP2A2-009 1009355-1010237 retained_intron
  ENST00000529427 AP2A2-011 1006544-1008282 retained_intron
  ENST00000529438 AP2A2-024 1001326-1009366 processed_transcript
  ENST00000529818 AP2A2-021 924894-977193 processed_transcript
  ENST00000529858 AP2A2-008 925870-970233 processed_transcript
  ENST00000530801 AP2A2-022 943100-972191 protein_coding
  ENST00000531497 AP2A2-005 1006709-1010926 retained_intron
  ENST00000531548 AP2A2-017 932693-977157 protein_coding
  ENST00000534328 AP2A2-004 925880-1010919 protein_coding
  ENST00000534485 AP2A2-018 933561-977207 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000332231ENST00000448903ENST00000528815ENST00000531497ENST00000534328ENST00000534485
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000332231 N/A N/A N/A 3.865±0.00 1.891±1.18 2.624±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000448903 5.835±0.00 6.945±0.00 2.040±0.00 13.008±0.00 6.987±0.00 5.016±3.00 1.969±1.53 8.420±5.15 2.987±1.64 0.721±0.00 2.497±1.75 9.240±5.68 11.528±0.00 11.162±0.02
ENST00000528815 15.656±0.00 7.320±0.00 2.088±0.00 6.597±1.98 6.285±3.62 4.196±0.75 3.666±2.71 9.475±6.23 5.574±3.24 6.061±3.94 8.063±0.00 13.526±8.57 19.625±2.07 24.521±7.01
ENST00000531497 N/A 2.031±0.00 N/A N/A 1.089±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000534328 N/A N/A N/A N/A N/A 3.731±0.00 0.795±0.00 N/A N/A N/A N/A N/A 10.761±0.00 13.899±0.00
ENST00000534485 N/A N/A N/A N/A N/A N/A N/A 10.803±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003EW CIL_0003EW_0001 CGP 11:867860-1012245
CIL_0003EX CIL_0003EX_0001 CGP 11:924894-1036706

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005905 IEA coated pit
GO:0006886 IEA intracellular protein transport
GO:0006897 IEA endocytosis
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0008289 IEA lipid binding
GO:0008565 IEA protein transporter activity
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0016032 TAS viral process
GO:0016192 IEA vesicle-mediated transport
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019901 ISS protein kinase binding
GO:0030117 IEA membrane coat
GO:0030131 IEA clathrin adaptor complex
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050690 TAS regulation of defense response to virus by virus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000002957 Ap2a2 adaptor-related protein complex 2, alpha 2 subunit protein_coding Mus_musculus

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