C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adaptor-related protein complex 2, alpha 2 subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000528815 AP2A2-002 ENSG00000183020 9606 + 11:925900-1010919 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000528815
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000528815 15.656±0.00 7.320±0.00 2.088±0.00 6.597±1.98 6.285±3.62 4.196±0.75 3.666±2.71 9.475±6.23 5.574±3.24 6.061±3.94 8.063±0.00 13.526±8.57 19.625±2.07 24.521±7.01

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003EW CIL_0003EW_0001 CGP 11:867860-1012245
CIL_0003EX CIL_0003EX_0001 CGP 11:924894-1036706

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005905 IEA coated pit
GO:0006886 IEA intracellular protein transport
GO:0006897 IEA endocytosis
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0008289 IEA lipid binding
GO:0008565 IEA protein transporter activity
GO:0016032 TAS viral process
GO:0016192 IEA vesicle-mediated transport
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019901 ISS protein kinase binding
GO:0030117 IEA membrane coat
GO:0030131 IEA clathrin adaptor complex
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050690 TAS regulation of defense response to virus by virus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000003038 Ap2a2-201 protein_coding Mus_musculus 0 2248
ENSMUST00000085399 Ap2a1-201 protein_coding Mus_musculus 0 1450
ENSMUST00000167930 Ap2a1-202 protein_coding Mus_musculus 0 1450
ENSMUST00000107857 Ap2a1-002 protein_coding Mus_musculus 0 1450
ENSMUST00000166972 Ap2a1-001 protein_coding Mus_musculus 0 1450
ENSDART00000076469 ap2a1-201 protein_coding Danio_rerio 0 1290
ENSDART00000155967 ap2a1-001 protein_coding Danio_rerio 0 1290
ENSMUST00000164575 Ap2a1-004 nonsense_mediated_decay Mus_musculus 0 451

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