C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: adaptor-related protein complex 2, alpha 2 subunit
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000448903 AP2A2-001 ENSG00000183020 9606 + 11:925881-1012239 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000448903
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000448903 5.835±0.00 6.945±0.00 2.040±0.00 13.008±0.00 6.987±0.00 5.016±3.00 1.969±1.53 8.420±5.15 2.987±1.64 0.721±0.00 2.497±1.75 9.240±5.68 11.528±0.00 11.162±0.02

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003EW CIL_0003EW_0001 CGP 11:867860-1012245
CIL_0003EX CIL_0003EX_0001 CGP 11:924894-1036706

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005488 IEA binding
GO:0005515 IPI protein binding
GO:0005829 TAS cytosol
GO:0005886 TAS plasma membrane
GO:0005905 IEA coated pit
GO:0006886 IEA intracellular protein transport
GO:0006897 IEA endocytosis
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007268 TAS synaptic transmission
GO:0007411 TAS axon guidance
GO:0008289 IEA lipid binding
GO:0008565 IEA protein transporter activity
GO:0015031 IEA protein transport
GO:0016020 IEA membrane
GO:0016032 TAS viral process
GO:0016192 IEA vesicle-mediated transport
GO:0019886 TAS antigen processing and presentation of exogenous peptide antigen via MHC class II
GO:0019901 ISS protein kinase binding
GO:0030117 IEA membrane coat
GO:0030131 IEA clathrin adaptor complex
GO:0030666 TAS endocytic vesicle membrane
GO:0030669 TAS clathrin-coated endocytic vesicle membrane
GO:0042059 TAS negative regulation of epidermal growth factor receptor signaling pathway
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050690 TAS regulation of defense response to virus by virus

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000003038 Ap2a2-201 protein_coding Mus_musculus 0 3258
ENSMUST00000085399 Ap2a1-201 protein_coding Mus_musculus 0 1441
ENSMUST00000167930 Ap2a1-202 protein_coding Mus_musculus 0 1441
ENSMUST00000107857 Ap2a1-002 protein_coding Mus_musculus 0 1441
ENSMUST00000166972 Ap2a1-001 protein_coding Mus_musculus 0 1441
ENSDART00000076469 ap2a1-201 protein_coding Danio_rerio 0 1280
ENSDART00000155967 ap2a1-001 protein_coding Danio_rerio 0 1280
ENSMUST00000164575 Ap2a1-004 nonsense_mediated_decay Mus_musculus 0 444

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