C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dopamine receptor D1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000184845 DRD1 9606 - 5:175440039-175444208 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000393752 DRD1-001 175440039-175444208 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonKidneyLiverLungOvaryPlacentaTestisENST00000393752
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Kidney Liver Lung Ovary Placenta Testis
ENST00000393752 0.035±0.00 0.218±0.00 0.043±0.00 0.871±0.36 0.546±0.00 0.147±0.11 0.102±0.01 0.105±0.07 0.453±0.32 0.265±0.15 0.239±0.15 0.085±0.08

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006Z0 CIL_0006Z0_0001 CGP 5:175440039-175529742

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001588 IMP dopamine neurotransmitter receptor activity, coupled via Gs
GO:0001659 IEA temperature homeostasis
GO:0001661 IEA conditioned taste aversion
GO:0001662 IEA behavioral fear response
GO:0001963 IEA synaptic transmission, dopaminergic
GO:0001975 IEA response to amphetamine
GO:0004930 IEA G-protein coupled receptor activity
GO:0004952 IDA dopamine neurotransmitter receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005783 IEA endoplasmic reticulum
GO:0005886 IDA plasma membrane
GO:0005887 IC integral component of plasma membrane
GO:0006606 IEA protein import into nucleus
GO:0006936 IEA muscle contraction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007187 IDA G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007189 IDA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190 IDA activation of adenylate cyclase activity
GO:0007191 IDA adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007212 IEA dopamine receptor signaling pathway
GO:0007416 ISS synapse assembly
GO:0007612 IEA learning
GO:0007613 IEA memory
GO:0007617 ISS mating behavior
GO:0007625 IEA grooming behavior
GO:0007626 IEA locomotory behavior
GO:0007628 ISS adult walking behavior
GO:0007631 IEA feeding behavior
GO:0008306 IEA associative learning
GO:0008542 ISS visual learning
GO:0010579 IEA positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0014002 IEA astrocyte development
GO:0015872 IEA dopamine transport
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0019226 ISS transmission of nerve impulse
GO:0019228 IEA neuronal action potential
GO:0021542 IEA dentate gyrus development
GO:0021756 IEA striatum development
GO:0021766 IEA hippocampus development
GO:0021853 ISS cerebral cortex GABAergic interneuron migration
GO:0030335 ISS positive regulation of cell migration
GO:0030432 IEA peristalsis
GO:0030819 IDA positive regulation of cAMP biosynthetic process
GO:0035106 IEA operant conditioning
GO:0035240 IMP dopamine binding
GO:0042053 IEA regulation of dopamine metabolic process
GO:0042220 IEA response to cocaine
GO:0042311 IEA vasodilation
GO:0042417 IC dopamine metabolic process
GO:0042493 ISS response to drug
GO:0042711 IEA maternal behavior
GO:0043268 ISS positive regulation of potassium ion transport
GO:0046323 IEA glucose import
GO:0046959 IEA habituation
GO:0046960 IEA sensitization
GO:0048148 IEA behavioral response to cocaine
GO:0051281 IDA positive regulation of release of sequestered calcium ion into cytosol
GO:0051482 IDA positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0051584 IC regulation of dopamine uptake involved in synaptic transmission
GO:0051968 ISS positive regulation of synaptic transmission, glutamatergic
GO:0060134 ISS prepulse inhibition
GO:0060158 IDA phospholipase C-activating dopamine receptor signaling pathway
GO:0060291 IEA long-term synaptic potentiation
GO:0060292 IEA long term synaptic depression
GO:0071870 IDA cellular response to catecholamine stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038918 drd1b dopamine receptor D1b protein_coding Danio_rerio
ENSDARG00000071640 CT025914.2 Uncharacterized protein protein_coding Danio_rerio
ENSMUSG00000021478 Drd1a dopamine receptor D1A protein_coding Mus_musculus

Loading