C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dopamine receptor D1A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021478 Drd1a 10090 - 13:54051186-54055658 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021932 Drd1a-201 54051186-54055658 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000021932
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021932 0.206±0.08 0.035±0.00 0.064±0.00 2.103±2.30 0.097±0.05 0.051±0.01 0.045±0.01 0.037±0.02 0.010±0.01 0.013±0.00 0.035±0.02 0.172±0.16 0.021±0.02 0.012±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006Z0 CIL_0006Z0_0002 CGP 13:54051186-54108346

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001588 IDA dopamine neurotransmitter receptor activity, coupled via Gs
GO:0001659 IMP temperature homeostasis
GO:0001661 IMP conditioned taste aversion
GO:0001662 IMP behavioral fear response
GO:0001963 IMP synaptic transmission, dopaminergic
GO:0001975 IMP response to amphetamine
GO:0004930 IDA G-protein coupled receptor activity
GO:0004952 IDA dopamine neurotransmitter receptor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005783 IEA endoplasmic reticulum
GO:0005886 IEA plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006606 IMP protein import into nucleus
GO:0006936 IMP muscle contraction
GO:0007186 IMP G-protein coupled receptor signaling pathway
GO:0007187 IEA G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007189 IEA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190 IDA activation of adenylate cyclase activity
GO:0007191 IDA adenylate cyclase-activating dopamine receptor signaling pathway
GO:0007212 IGI dopamine receptor signaling pathway
GO:0007612 IMP learning
GO:0007613 IMP memory
GO:0007617 IDA mating behavior
GO:0007625 IMP grooming behavior
GO:0007626 IMP locomotory behavior
GO:0007628 IGI adult walking behavior
GO:0007631 IGI feeding behavior
GO:0008306 IMP associative learning
GO:0008542 IMP visual learning
GO:0010579 IEA positive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0014002 IMP astrocyte development
GO:0015872 IMP dopamine transport
GO:0016020 IDA membrane
GO:0019226 IMP transmission of nerve impulse
GO:0019228 IMP neuronal action potential
GO:0021542 IMP dentate gyrus development
GO:0021756 IMP striatum development
GO:0021766 IMP hippocampus development
GO:0021853 IMP cerebral cortex GABAergic interneuron migration
GO:0030335 IMP positive regulation of cell migration
GO:0030432 IGI peristalsis
GO:0030819 IEA positive regulation of cAMP biosynthetic process
GO:0035106 IMP operant conditioning
GO:0035240 IEA dopamine binding
GO:0042053 IMP regulation of dopamine metabolic process
GO:0042220 IMP response to cocaine
GO:0042311 IEA vasodilation
GO:0042493 IMP response to drug
GO:0042711 IMP maternal behavior
GO:0046323 IMP glucose import
GO:0046959 IMP habituation
GO:0046960 IGI sensitization
GO:0048148 IMP behavioral response to cocaine
GO:0051281 IEA positive regulation of release of sequestered calcium ion into cytosol
GO:0051482 IEA positive regulation of cytosolic calcium ion concentration involved in phospholipase C-activating G-protein coupled signaling pathway
GO:0051968 IMP positive regulation of synaptic transmission, glutamatergic
GO:0060158 IDA phospholipase C-activating dopamine receptor signaling pathway
GO:0060291 IMP long-term synaptic potentiation
GO:0060292 IMP long term synaptic depression
GO:0071870 IEA cellular response to catecholamine stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000038918 drd1b dopamine receptor D1b protein_coding Danio_rerio
ENSDARG00000071640 CT025914.2 Uncharacterized protein protein_coding Danio_rerio
ENSG00000184845 DRD1 dopamine receptor D1 protein_coding Homo_sapiens

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