C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: negative elongation factor complex member A
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185049 NELFA 9606 - 4:1982714-2041903 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000333877 NELFA-002 1982730-2009183 nonsense_mediated_decay
  ENST00000382882 NELFA-001 1982714-2010110 protein_coding
  ENST00000411638 NELFA-015 1982723-2008975 protein_coding
  ENST00000411649 NELFA-010 1987942-2008835 protein_coding
  ENST00000416258 NELFA-003 1982730-1992624 protein_coding
  ENST00000421397 NELFA-009 1986382-2008848 nonsense_mediated_decay
  ENST00000431323 NELFA-006 1986114-2008997 protein_coding
  ENST00000443203 NELFA-007 1991588-2008972 nonsense_mediated_decay
  ENST00000453740 NELFA-012 1984808-1990501 protein_coding
  ENST00000455762 NELFA-011 1986115-2041903 protein_coding
  ENST00000458616 NELFA-008 2003838-2008942 nonsense_mediated_decay
  ENST00000463820 NELFA-004 1982730-1992244 retained_intron
  ENST00000467661 NELFA-005 1982723-1986560 retained_intron
  ENST00000484545 NELFA-014 1987501-1989756 retained_intron
  ENST00000488452 NELFA-013 1986280-1990054 retained_intron
  ENST00000542778 NELFA-201 1982717-2009235 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000333877ENST00000382882ENST00000411638ENST00000411649ENST00000421397ENST00000431323ENST00000443203ENST00000453740ENST00000463820ENST00000467661ENST00000484545ENST00000542778
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000333877 N/A N/A N/A N/A N/A N/A 1.002±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000382882 N/A N/A N/A 0.207±0.00 N/A N/A N/A N/A 0.207±0.00 N/A N/A N/A N/A N/A
ENST00000411638 11.356±0.00 13.801±0.00 0.487±0.00 3.349±3.05 7.647±0.00 3.672±2.48 1.948±0.00 6.210±0.00 1.627±0.56 4.753±4.15 11.457±0.00 19.745±3.12 13.362±2.87 17.228±1.83
ENST00000411649 N/A N/A 1.053±0.00 0.989±0.00 1.042±0.00 N/A N/A N/A N/A N/A N/A 1.544±0.00 N/A N/A
ENST00000421397 N/A N/A N/A 1.171±0.00 N/A N/A 0.179±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000431323 N/A N/A N/A N/A N/A N/A N/A N/A 0.784±0.00 1.568±0.00 N/A N/A N/A N/A
ENST00000443203 N/A N/A 1.053±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000453740 N/A N/A N/A 12.151±0.00 N/A 2.950±2.16 0.169±0.00 10.948±0.00 N/A N/A N/A 0.668±0.00 4.331±0.00 21.904±7.69
ENST00000463820 N/A N/A N/A N/A 1.361±1.19 1.279±0.00 0.132±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000467661 N/A N/A N/A 0.291±0.00 N/A N/A N/A 1.284±0.00 0.865±0.00 N/A N/A 0.229±0.00 N/A 6.400±0.00
ENST00000484545 N/A N/A N/A N/A N/A N/A N/A 2.034±0.00 N/A N/A N/A N/A N/A N/A
ENST00000542778 N/A N/A N/A N/A N/A N/A 0.704±0.00 N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006V9 CIL_0006V9_0001 CGP 4:1871424-2041903
CIL_0006V6 CIL_0006V6_0001 CGP 4:1982714-2043970

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003682 IEA chromatin binding
GO:0003746 IEA translation elongation factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005737 IDA cytoplasm
GO:0006366 TAS transcription from RNA polymerase II promoter
GO:0006368 TAS transcription elongation from RNA polymerase II promoter
GO:0006414 IEA translational elongation
GO:0007275 TAS multicellular organismal development
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0032021 IEA NELF complex
GO:0034244 IEA negative regulation of transcription elongation from RNA polymerase II promoter
GO:0050434 TAS positive regulation of viral transcription

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000061411 nelfa negative elongation factor complex member A protein_coding Danio_rerio
ENSMUSG00000029111 Nelfa negative elongation factor complex member A, Whsc2 protein_coding Mus_musculus

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