C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sodium channel, voltage-gated, type X, alpha subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185313 SCN10A 9606 - 3:38696802-38794010 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000449082 SCN10A-001 38696802-38794010 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalHeartLungOvaryPlacentaTestisENST00000449082
Transcript ID Adrenal Heart Lung Ovary Placenta Testis
ENST00000449082 0.005±0.00 0.029±0.01 0.009±0.00 0.005±0.00 0.024±0.01 0.065±0.05

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BE CIL_0008BE_0001 VISTA 3:38261144-38866061
CIL_0004RF CIL_0004RF_0001 CGP 3:38548057-38794010
CIL_0004RE CIL_0004RE_0001 CGP 3:38696802-38950561

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001518 IDA:IEA voltage-gated sodium channel complex
GO:0002027 IMP regulation of heart rate
GO:0005216 IEA ion channel activity
GO:0005248 IDA:IEA voltage-gated sodium channel activity
GO:0005886 IEA plasma membrane
GO:0006811 IEA ion transport
GO:0006814 TAS:IEA sodium ion transport
GO:0007600 TAS sensory perception
GO:0016020 IEA membrane
GO:0019228 IBA neuronal action potential
GO:0019233 IEA sensory perception of pain
GO:0030424 IEA axon
GO:0034765 IDA regulation of ion transmembrane transport
GO:0035725 IDA sodium ion transmembrane transport
GO:0044299 IEA C-fiber
GO:0055085 IEA transmembrane transport
GO:0055117 IMP regulation of cardiac muscle contraction
GO:0060371 IMP regulation of atrial cardiac muscle cell membrane depolarization
GO:0061337 IEA cardiac conduction
GO:0070062 IDA extracellular vesicular exosome
GO:0086010 IBA membrane depolarization during action potential
GO:0086067 IMP AV node cell to bundle of His cell communication
GO:0086069 IMP bundle of His cell to Purkinje myocyte communication

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078758 SCN11A sodium channel, voltage-gated, type XI, alpha subunit protein_coding Danio_rerio
ENSMUSG00000034533 Scn10a sodium channel, voltage-gated, type X, alpha protein_coding Mus_musculus

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