C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: sodium channel, voltage-gated, type X, alpha
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000034533 Scn10a 10090 - 9:119608456-119719032 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000084787 Scn10a-201 119608456-119719032 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENSMUST00000084787
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENSMUST00000084787 0.013±0.00 0.002±0.00 0.108±0.05 0.007±0.00 0.027±0.00 0.134±0.08 0.004±0.00 0.043±0.02 0.122±0.08 0.203±0.08 0.010±0.00 0.133±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008BE CIL_0008BE_0002 VISTA 9:119196374-119798584
CIL_0004RF CIL_0004RF_0002 CGP 9:119483408-119719032
CIL_0004RE CIL_0004RE_0002 CGP 9:119608456-119825456

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002027 IEA regulation of heart rate
GO:0005248 IDA voltage-gated sodium channel activity
GO:0005886 IDA plasma membrane
GO:0006814 IDA sodium ion transport
GO:0019228 IBA neuronal action potential
GO:0019233 IEA sensory perception of pain
GO:0030424 IDA axon
GO:0034765 IEA regulation of ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0044299 IDA C-fiber
GO:0055117 IEA regulation of cardiac muscle contraction
GO:0060371 IMP regulation of atrial cardiac muscle cell membrane depolarization
GO:0061337 IMP cardiac conduction
GO:0070062 IEA extracellular vesicular exosome
GO:0086010 IBA membrane depolarization during action potential
GO:0086067 IEA AV node cell to bundle of His cell communication
GO:0086069 IEA bundle of His cell to Purkinje myocyte communication

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000078758 SCN11A sodium channel, voltage-gated, type XI, alpha subunit protein_coding Danio_rerio
ENSG00000185313 SCN10A sodium channel, voltage-gated, type X, alpha subunit protein_coding Homo_sapiens

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