C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: SH3 domain binding glutamate-rich protein
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185437 SH3BGR 9606 + 21:39445855-39515506 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000333634 SH3BGR-001 39451830-39515506 protein_coding
  ENST00000380631 SH3BGR-006 39445942-39515207 protein_coding
  ENST00000380634 SH3BGR-007 39445865-39515355 protein_coding
  ENST00000380637 SH3BGR-002 39445855-39515506 protein_coding
  ENST00000423596 SH3BGR-010 39462534-39511775 protein_coding
  ENST00000440288 SH3BGR-005 39445931-39511706 protein_coding
  ENST00000447939 SH3BGR-009 39499823-39515506 protein_coding
  ENST00000452550 SH3BGR-008 39452123-39515506 protein_coding
  ENST00000458295 SH3BGR-004 39445875-39515270 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000333634ENST00000380631ENST00000380634ENST00000380637ENST00000423596ENST00000440288ENST00000447939ENST00000452550ENST00000458295
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000333634 N/A 0.375±0.00 N/A 1.589±1.37 4.058±0.00 5.345±4.53 10.597±6.84 1.216±0.00 1.864±1.73 0.336±0.21 18.350±4.40 0.835±0.42 0.603±0.19 2.699±0.00
ENST00000380631 N/A N/A 0.296±0.00 1.964±1.66 N/A 0.266±0.00 8.000±0.00 N/A 0.494±0.00 N/A N/A 0.841±0.38 0.343±0.00 1.451±0.00
ENST00000380634 0.275±0.00 1.385±0.00 N/A 3.234±2.74 6.666±0.00 12.580±0.00 10.874±0.00 1.658±0.56 0.340±0.00 1.740±0.00 36.522±0.00 N/A 0.369±0.11 3.051±1.43
ENST00000380637 N/A N/A N/A 2.418±2.12 0.296±0.00 N/A N/A N/A N/A 0.773±0.00 N/A 0.651±0.46 N/A 2.461±0.22
ENST00000423596 1.078±0.00 4.461±0.00 N/A N/A 12.716±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000440288 0.369±0.00 N/A N/A N/A N/A N/A N/A 1.789±0.00 N/A N/A N/A 1.309±0.02 1.260±0.60 11.576±0.00
ENST00000447939 0.268±0.00 N/A N/A N/A N/A N/A N/A 1.441±0.00 0.724±0.00 N/A 16.270±0.00 N/A 0.574±0.00 3.542±0.00
ENST00000452550 N/A N/A N/A N/A N/A N/A 0.830±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000458295 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 3.133±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004WM CIL_0004WM_0001 CGP 21:39405844-39515506
CIL_0005QK CIL_0005QK_0001 CGP 21:39445855-39673137

Gene Ontology

GO IDEvidence TypeGO Description
GO:0005070 TAS SH3/SH2 adaptor activity
GO:0005829 IDA cytosol
GO:0006461 TAS protein complex assembly
GO:0009967 TAS positive regulation of signal transduction
GO:0017124 IEA SH3 domain binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000021633 sh3bgr SH3 domain binding glutamic acid-rich protein protein_coding Danio_rerio
ENSMUSG00000040666 Sh3bgr SH3-binding domain glutamic acid-rich protein protein_coding Mus_musculus

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