C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: IKAROS family zinc finger 1 (Ikaros)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185811 IKZF1 9606 + 7:50304124-50405101 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000331340 IKZF1-001 50304782-50405101 protein_coding
  ENST00000343574 IKZF1-201 50304782-50405098 protein_coding
  ENST00000346667 IKZF1-202 50304782-50405098 protein_coding
  ENST00000349824 IKZF1-203 50304782-50405098 protein_coding
  ENST00000357364 IKZF1-204 50304782-50405098 protein_coding
  ENST00000359197 IKZF1-002 50304782-50402525 protein_coding
  ENST00000413698 IKZF1-007 50304728-50369444 protein_coding
  ENST00000426121 IKZF1-006 50327649-50400009 protein_coding
  ENST00000438033 IKZF1-003 50308721-50400876 protein_coding
  ENST00000439701 IKZF1-004 50308722-50402566 protein_coding
  ENST00000440768 IKZF1-205 50304782-50405098 protein_coding
  ENST00000462201 IKZF1-011 50308754-50377327 retained_intron
  ENST00000471793 IKZF1-005 50327379-50400627 retained_intron
  ENST00000484847 IKZF1-008 50304124-50327985 processed_transcript
  ENST00000492119 IKZF1-010 50367665-50369704 processed_transcript
  ENST00000492782 IKZF1-009 50308748-50369839 processed_transcript
  ENST00000612658 IKZF1-206 50304782-50400627 protein_coding
  ENST00000615491 IKZF1-207 50304782-50405098 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000331340ENST00000343574ENST00000346667ENST00000349824ENST00000357364ENST00000359197ENST00000413698ENST00000439701ENST00000440768ENST00000462201ENST00000471793ENST00000615491
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000331340 N/A N/A N/A N/A 0.195±0.00 0.359±0.00 0.084±0.03 0.086±0.00 0.284±0.13 N/A N/A 0.174±0.05 0.273±0.09 0.290±0.00
ENST00000343574 0.475±0.00 6.465±0.00 N/A 0.297±0.00 N/A 0.496±0.00 N/A 0.276±0.00 0.575±0.00 0.743±0.00 N/A N/A N/A 0.381±0.00
ENST00000346667 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.671±0.00 0.127±0.02 0.379±0.05 N/A 0.353±0.25
ENST00000349824 N/A N/A N/A N/A N/A 0.097±0.00 N/A N/A 0.096±0.00 0.694±0.00 N/A N/A N/A N/A
ENST00000357364 0.556±0.00 5.827±0.00 N/A 0.172±0.00 0.540±0.00 N/A N/A 0.238±0.00 0.297±0.00 0.652±0.00 N/A 0.140±0.00 0.441±0.04 N/A
ENST00000359197 N/A N/A 0.377±0.00 N/A N/A N/A 0.227±0.00 N/A N/A 1.457±0.00 N/A N/A N/A N/A
ENST00000413698 N/A N/A 0.165±0.00 0.180±0.00 N/A 1.132±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000439701 N/A N/A N/A N/A N/A N/A 0.043±0.00 0.422±0.00 N/A N/A N/A N/A N/A N/A
ENST00000440768 N/A N/A N/A N/A N/A 0.089±0.00 N/A N/A 0.098±0.00 N/A N/A N/A N/A N/A
ENST00000462201 N/A N/A 0.245±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000471793 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.586±0.00 N/A N/A
ENST00000615491 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.516±0.00 0.285±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XP CIL_0008XP_0001 VISTA 7:49879868-50480692
CIL_0008P3 CIL_0008P3_0001 VISTA 7:49993452-50594868
CIL_0008XT CIL_0008XT_0001 VISTA 7:50018042-50619048
CIL_0007SD CIL_0007SD_0001 VISTA 7:50081734-50682493
CIL_0007MQ CIL_0007MQ_0001 UCNEbase 7:50180166-50331035
CIL_00089U CIL_00089U_0001 VISTA 7:50196544-50798008
CIL_000642 CIL_000642_0001 CGP 7:50304124-50542535

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001779 IEA natural killer cell differentiation
GO:0003677 TAS DNA binding
GO:0003700 IEA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005721 IEA pericentric heterochromatin
GO:0005737 IEA cytoplasm
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0007049 IEA cell cycle
GO:0007498 TAS mesoderm development
GO:0016568 IEA chromatin modification
GO:0030097 IEA hemopoiesis
GO:0030183 IEA B cell differentiation
GO:0030217 IEA T cell differentiation
GO:0030900 IEA forebrain development
GO:0040018 IEA positive regulation of multicellular organism growth
GO:0043565 IEA sequence-specific DNA binding
GO:0045660 IEA positive regulation of neutrophil differentiation
GO:0045892 IEA negative regulation of transcription, DNA-templated
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IEA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0046982 IEA protein heterodimerization activity
GO:0048535 IEA lymph node development
GO:0048538 IEA thymus development
GO:0048541 IEA Peyer's patch development
GO:0048732 IEA gland development
GO:0051138 IEA positive regulation of NK T cell differentiation
GO:0060041 IEA retina development in camera-type eye

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013539 ikzf1 IKAROS family zinc finger 1 (Ikaros) protein_coding Danio_rerio
ENSMUSG00000018654 Ikzf1 IKAROS family zinc finger 1 protein_coding Mus_musculus

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