C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: IKAROS family zinc finger 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000018654 Ikzf1 10090 + 11:11685003-11772926 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000018798 Ikzf1-003 11686445-11769798 protein_coding
  ENSMUST00000048122 Ikzf1-004 11686229-11761424 protein_coding
  ENSMUST00000065433 Ikzf1-002 11685925-11772112 protein_coding
  ENSMUST00000076700 Ikzf1-201 11686213-11772926 protein_coding
  ENSMUST00000126058 Ikzf1-001 11685003-11754083 protein_coding
  ENSMUST00000141436 Ikzf1-005 11685003-11707800 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000018798ENSMUST00000048122ENSMUST00000065433ENSMUST00000076700
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000018798 2.590±0.22 1.901±0.09 0.467±0.00 0.672±0.14 45.954±20.94 3.644±0.48 0.546±0.28 1.736±0.87 6.158±7.79 9.221±1.47 N/A 3.600±0.70 0.628±0.00 0.331±0.26
ENSMUST00000048122 N/A 2.839±0.84 N/A N/A N/A 1.936±0.00 N/A N/A 0.247±0.00 N/A N/A N/A N/A N/A
ENSMUST00000065433 0.654±0.04 N/A 0.325±0.08 0.250±0.00 7.016±2.78 0.593±0.00 0.361±0.06 0.357±0.09 2.834±2.18 1.267±0.38 0.307±0.44 0.403±0.14 0.284±0.08 0.074±0.04
ENSMUST00000076700 0.599±0.17 0.730±0.20 0.682±0.05 0.203±0.08 7.742±3.68 0.727±0.12 0.199±0.04 0.662±0.32 6.524±6.51 2.619±0.62 0.162±0.22 0.673±0.25 0.277±0.16 0.096±0.04

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008XP CIL_0008XP_0002 VISTA 11:11227967-11828770
CIL_0008P3 CIL_0008P3_0002 VISTA 11:11375621-11977027
CIL_0008XT CIL_0008XT_0002 VISTA 11:11399170-12000205
CIL_0007SD CIL_0007SD_0002 VISTA 11:11453227-12053958
CIL_0007MQ CIL_0007MQ_0003 UCNEbase 11:11528251-11753919
CIL_00089U CIL_00089U_0002 VISTA 11:11536402-12137998
CIL_0008KL CIL_0008KL_0002 VISTA 11:11661856-12262621
CIL_000642 CIL_000642_0002 CGP 11:11685003-11808962

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0001779 IMP natural killer cell differentiation
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0005667 TAS transcription factor complex
GO:0005721 IDA pericentric heterochromatin
GO:0006355 IMP regulation of transcription, DNA-templated
GO:0030097 IMP hemopoiesis
GO:0030183 IMP B cell differentiation
GO:0030217 IMP T cell differentiation
GO:0030900 IMP forebrain development
GO:0040018 IGI positive regulation of multicellular organism growth
GO:0043565 IMP sequence-specific DNA binding
GO:0045660 IMP positive regulation of neutrophil differentiation
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:0045893 IDA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046872 IEA metal ion binding
GO:0046982 IPI protein heterodimerization activity
GO:0048535 IMP lymph node development
GO:0048538 IMP thymus development
GO:0048541 IMP Peyer's patch development
GO:0048732 IMP gland development
GO:0051138 IMP positive regulation of NK T cell differentiation
GO:0060041 IMP retina development in camera-type eye

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000013539 ikzf1 IKAROS family zinc finger 1 (Ikaros) protein_coding Danio_rerio
ENSG00000185811 IKZF1 IKAROS family zinc finger 1 (Ikaros) protein_coding Homo_sapiens

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