C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: interferon induced transmembrane protein 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185885 IFITM1 9606 + 11:313506-315272 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000328221 IFITM1-003 313527-315240 protein_coding
  ENST00000408968 IFITM1-001 313853-315272 protein_coding
  ENST00000525554 IFITM1-004 314418-314962 processed_transcript
  ENST00000528780 IFITM1-002 313506-315272 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000328221ENST00000408968ENST00000528780
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000328221 75.033±0.00 143.171±0.00 N/A 20.914±0.00 71.953±0.00 121.879±0.00 65.031±0.00 81.210±0.00 N/A 234.993±0.00 24.038±20.85 120.757±0.00 57.960±0.00 132.230±0.00
ENST00000408968 109.748±0.00 66.237±0.00 1.150±0.00 9.620±5.87 18.644±0.00 7.077±0.00 4.215±0.00 9.996±0.00 5.347±0.00 9.787±0.00 N/A 110.037±127.26 23.107±0.00 5.702±0.00
ENST00000528780 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 122.876±0.00 78.546±11.79 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UF CIL_0002UF_0001 CGP 11:298200-315272
CIL_0002UG CIL_0002UG_0001 CGP 11:307631-315272
CIL_0002UG CIL_0002UG_0002 CGP 11:313506-327537

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0005057 TAS receptor signaling protein activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0007166 TAS cell surface receptor signaling pathway
GO:0008285 IMP negative regulation of cell proliferation
GO:0009607 IEA response to biotic stimulus
GO:0009615 IDA response to virus
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030336 IMP negative regulation of cell migration
GO:0034341 IDA response to interferon-gamma
GO:0035455 IDA response to interferon-alpha
GO:0035456 IDA response to interferon-beta
GO:0035556 TAS intracellular signal transduction
GO:0045071 IDA negative regulation of viral genome replication
GO:0045669 IMP positive regulation of osteoblast differentiation
GO:0046597 IDA negative regulation of viral entry into host cell
GO:0050776 TAS regulation of immune response
GO:0051607 IEA defense response to virus
GO:0060337 TAS type I interferon signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000093303 si:dkey-226m8.7 interferon induced transmembrane protein 3 protein_coding Danio_rerio
ENSMUSG00000025491 Ifitm1 interferon induced transmembrane protein 1 protein_coding Mus_musculus
ENSMUSG00000025492 Ifitm3 interferon induced transmembrane protein 3 protein_coding Mus_musculus
ENSMUSG00000060591 Ifitm2 interferon induced transmembrane protein 2 protein_coding Mus_musculus
ENSMUSG00000065968 Ifitm7 interferon induced transmembrane protein 7 protein_coding Mus_musculus
ENSMUSG00000068631 Gm7676 predicted gene 7676 protein_coding Mus_musculus

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