C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: interferon induced transmembrane protein 1
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000408968 IFITM1-001 ENSG00000185885 9606 + 11:313853-315272 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000408968
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000408968 109.748±0.00 66.237±0.00 1.150±0.00 9.620±5.87 18.644±0.00 7.077±0.00 4.215±0.00 9.996±0.00 5.347±0.00 9.787±0.00 110.037±127.26 23.107±0.00 5.702±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002UF CIL_0002UF_0001 CGP 11:298200-315272
CIL_0002UG CIL_0002UG_0001 CGP 11:307631-315272
CIL_0002UG CIL_0002UG_0002 CGP 11:313506-327537

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001503 IEA ossification
GO:0005057 TAS receptor signaling protein activity
GO:0005515 IPI protein binding
GO:0005886 TAS plasma membrane
GO:0007166 TAS cell surface receptor signaling pathway
GO:0008285 IMP negative regulation of cell proliferation
GO:0009607 IEA response to biotic stimulus
GO:0009615 IDA response to virus
GO:0016020 IDA membrane
GO:0016021 IEA integral component of membrane
GO:0019221 TAS cytokine-mediated signaling pathway
GO:0030336 IMP negative regulation of cell migration
GO:0034341 IDA response to interferon-gamma
GO:0035455 IDA response to interferon-alpha
GO:0035456 IDA response to interferon-beta
GO:0035556 TAS intracellular signal transduction
GO:0045071 IDA negative regulation of viral genome replication
GO:0045669 IMP positive regulation of osteoblast differentiation
GO:0046597 IDA negative regulation of viral entry into host cell
GO:0050776 TAS regulation of immune response
GO:0051607 IEA defense response to virus
GO:0060337 TAS type I interferon signaling pathway

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000026564 Ifitm1-003 protein_coding Mus_musculus 0 215
ENSMUST00000106040 Ifitm1-002 protein_coding Mus_musculus 0 215
ENSMUST00000106042 Ifitm1-001 protein_coding Mus_musculus 0 215

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