C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: protein kinase, cAMP-dependent, regulatory, type I, beta
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000537384 PRKAR1B-201 ENSG00000188191 9606 - 7:549197-727341 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000537384
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000537384 2.914±0.00 13.267±0.00 203.680±0.00 10.293±0.00 15.253±0.00 8.445±0.00 7.099±0.00 3.046±0.00 3.555±2.65 23.321±10.15 7.124±1.94 9.871±5.19

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00018I CIL_00018I_0001 CGP 7:497258-727650
CIL_00018H CIL_00018H_0001 CGP 7:549197-786475

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001932 IEA regulation of protein phosphorylation
GO:0004862 IDA cAMP-dependent protein kinase inhibitor activity
GO:0005829 TAS cytosol
GO:0005886 IEA plasma membrane
GO:0005952 IEA:NAS cAMP-dependent protein kinase complex
GO:0006112 TAS energy reserve metabolic process
GO:0006468 NAS protein phosphorylation
GO:0006833 TAS water transport
GO:0007165 TAS signal transduction
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007596 TAS blood coagulation
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0008603 IEA:NAS cAMP-dependent protein kinase regulator activity
GO:0030552 IEA cAMP binding
GO:0034199 TAS activation of protein kinase A activity
GO:0034236 IPI protein kinase A catalytic subunit binding
GO:0044281 TAS small molecule metabolic process
GO:0045087 TAS innate immune response
GO:0045859 IEA regulation of protein kinase activity
GO:0048011 TAS neurotrophin TRK receptor signaling pathway
GO:0050796 TAS regulation of insulin secretion
GO:0055085 TAS transmembrane transport
GO:0071377 TAS cellular response to glucagon stimulus
GO:2000480 IDA negative regulation of cAMP-dependent protein kinase activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSDART00000091513 prkar1b-201 protein_coding Danio_rerio 0 963
ENSDART00000132529 prkar1b-001 protein_coding Danio_rerio 0 544

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