C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine/arginine-rich splicing factor 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000188529 SRSF10 9606 - 1:23964804-23980927 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000338597 SRSF10-008 23970975-23977937 processed_transcript
  ENST00000341154 SRSF10-004 23966445-23980927 processed_transcript
  ENST00000343255 SRSF10-003 23969083-23980327 protein_coding
  ENST00000344989 SRSF10-002 23964804-23980331 protein_coding
  ENST00000374452 SRSF10-006 23967307-23980308 protein_coding
  ENST00000374453 SRSF10-014 23967618-23980294 protein_coding
  ENST00000453840 SRSF10-005 23966445-23980296 protein_coding
  ENST00000469303 SRSF10-013 23978155-23978946 retained_intron
  ENST00000473754 SRSF10-016 23971369-23975052 processed_transcript
  ENST00000473858 SRSF10-015 23967301-23980331 nonsense_mediated_decay
  ENST00000484146 SRSF10-017 23967173-23980356 protein_coding
  ENST00000485292 SRSF10-010 23977790-23980331 processed_transcript
  ENST00000485841 SRSF10-007 23970379-23977652 retained_intron
  ENST00000492112 SRSF10-001 23970364-23980319 protein_coding
  ENST00000495785 SRSF10-012 23971339-23980271 nonsense_mediated_decay
  ENST00000497214 SRSF10-011 23977270-23978252 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000343255ENST00000344989ENST00000374452ENST00000374453ENST00000453840ENST00000473754ENST00000473858ENST00000485841ENST00000492112ENST00000495785
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000343255 6.150±0.00 5.890±0.00 4.788±0.00 4.534±0.00 5.961±0.00 3.846±0.00 5.348±3.90 3.570±0.00 4.038±0.78 4.245±0.00 8.385±1.67 4.806±0.60 8.832±0.00
ENST00000344989 N/A N/A 1.938±0.25 2.882±0.56 5.420±0.00 0.892±0.14 3.995±1.76 1.459±0.51 3.097±0.00 1.018±0.00 5.936±1.29 2.433±0.61 5.610±1.35
ENST00000374452 N/A N/A N/A N/A N/A N/A N/A N/A 6.310±0.00 N/A 11.703±0.00 N/A 14.682±0.00
ENST00000374453 N/A N/A N/A N/A N/A 3.574±0.00 N/A 5.585±0.00 N/A N/A N/A N/A N/A
ENST00000453840 6.752±0.00 8.146±0.00 N/A 7.012±0.00 4.827±0.00 4.678±0.00 11.732±0.00 7.007±0.00 4.434±0.00 1.659±0.29 9.513±2.34 6.646±0.50 13.087±1.47
ENST00000473754 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 10.356±0.00 N/A
ENST00000473858 N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.500±0.00 N/A N/A N/A
ENST00000485841 N/A 2.425±0.00 1.667±0.00 N/A N/A 1.195±0.00 1.748±0.00 2.435±0.00 2.944±0.00 0.475±0.00 N/A N/A N/A
ENST00000492112 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.350±0.00 N/A
ENST00000495785 N/A N/A N/A 4.685±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0000244 NAS spliceosomal tri-snRNP complex assembly
GO:0000375 IDA RNA splicing, via transesterification reactions
GO:0000398 IDA mRNA splicing, via spliceosome
GO:0003676 IEA nucleic acid binding
GO:0003723 NAS RNA binding
GO:0005515 IPI protein binding
GO:0005634 IC nucleus
GO:0005654 IDA nucleoplasm
GO:0005737 NAS cytoplasm
GO:0006355 NAS regulation of transcription, DNA-templated
GO:0006376 IDA mRNA splice site selection
GO:0006406 NAS mRNA export from nucleus
GO:0016482 IDA cytoplasmic transport
GO:0044822 IDA poly(A) RNA binding
GO:0048025 IDA negative regulation of mRNA splicing, via spliceosome
GO:0050733 NAS RS domain binding
GO:0051082 NAS unfolded protein binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022415 SRSF10 (1 of 2) serine/arginine-rich splicing factor 10 protein_coding Danio_rerio
ENSDARG00000086411 SRSF10 (2 of 2) serine/arginine-rich splicing factor 10 protein_coding Danio_rerio
ENSMUSG00000028676 Srsf10 serine/arginine-rich splicing factor 10 protein_coding Mus_musculus

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