C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: fragile histidine triad
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000189283 FHIT 9606 - 3:59749310-61251459 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000341848 FHIT-201 60011371-60014150 protein_coding
  ENST00000465330 FHIT-006 61244010-61251412 processed_transcript
  ENST00000466788 FHIT-005 59749702-60080840 processed_transcript
  ENST00000468189 FHIT-002 59751407-61251459 protein_coding
  ENST00000476844 FHIT-001 59749310-61251413 protein_coding
  ENST00000488467 FHIT-007 60014020-61251413 protein_coding
  ENST00000490952 FHIT-004 60535810-61251384 retained_intron
  ENST00000492590 FHIT-003 59749310-61251450 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000466788ENST00000468189ENST00000476844ENST00000490952ENST00000492590
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000466788 N/A 0.715±0.00 N/A 0.154±0.10 N/A N/A 0.080±0.00 N/A N/A N/A N/A 0.056±0.00 N/A 0.302±0.00
ENST00000468189 N/A N/A 0.829±0.00 0.100±0.00 N/A N/A N/A N/A N/A N/A N/A 0.248±0.00 N/A N/A
ENST00000476844 0.751±0.00 N/A N/A 2.519±2.20 1.592±0.00 1.293±0.00 1.602±0.00 1.821±1.40 1.021±0.15 1.713±0.00 1.332±0.00 1.530±1.08 1.026±0.32 1.217±0.00
ENST00000490952 N/A N/A 0.745±0.00 N/A 0.449±0.00 N/A 0.337±0.00 0.485±0.00 N/A N/A 0.193±0.00 0.083±0.00 N/A N/A
ENST00000492590 N/A N/A N/A 1.627±1.38 2.425±0.00 1.940±0.00 1.700±0.00 2.076±0.00 1.589±0.00 N/A N/A 0.915±0.62 1.371±0.19 1.577±0.41

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00034H CIL_00034H_0001 CGP 3:58717365-61251459

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0003824 IEA catalytic activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 IDA cytosol
GO:0006163 IDA purine nucleotide metabolic process
GO:0006260 IEA DNA replication
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0009117 TAS nucleotide metabolic process
GO:0016787 IDA hydrolase activity
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032435 IMP negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042802 IPI identical protein binding
GO:0047710 IDA bis(5'-adenosyl)-triphosphatase activity
GO:0070062 IDA extracellular vesicular exosome
GO:0072332 IMP intrinsic apoptotic signaling pathway by p53 class mediator

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000068850 fhit fragile histidine triad gene protein_coding Danio_rerio
ENSDARG00000078195 fhit fragile histidine triad gene protein_coding Danio_rerio
ENSMUSG00000060579 Fhit fragile histidine triad gene protein_coding Mus_musculus

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