C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: fragile histidine triad
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000492590 FHIT-003 ENSG00000189283 9606 - 3:59749310-61251450 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; BrainBreastColonHeartKidneyLiverOvaryPlacentaTestisENST00000492590
Transcript ID Brain Breast Colon Heart Kidney Liver Ovary Placenta Testis
ENST00000492590 1.627±1.38 2.425±0.00 1.940±0.00 1.700±0.00 2.076±0.00 1.589±0.00 0.915±0.62 1.371±0.19 1.577±0.41

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00034H CIL_00034H_0001 CGP 3:58717365-61251459

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0003824 TAS:IEA catalytic activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 IDA cytosol
GO:0006163 IDA purine nucleotide metabolic process
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0009117 TAS nucleotide metabolic process
GO:0016787 IDA hydrolase activity
GO:0031625 IPI ubiquitin protein ligase binding
GO:0032435 IMP negative regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0042802 IPI identical protein binding
GO:0047710 IDA bis(5'-adenosyl)-triphosphatase activity
GO:0070062 IDA extracellular vesicular exosome
GO:0072332 IMP intrinsic apoptotic signaling pathway by p53 class mediator

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000161302 Fhit-001 protein_coding Mus_musculus 0 492
ENSMUST00000162278 Fhit-003 protein_coding Mus_musculus 0 492
ENSMUST00000160340 Fhit-002 protein_coding Mus_musculus 0 492
ENSMUST00000179394 Fhit-201 protein_coding Mus_musculus 0 483
ENSMUST00000161895 Fhit-006 protein_coding Mus_musculus 0 444
ENSMUST00000161179 Fhit-005 retained_intron Mus_musculus 0 414
ENSMUST00000162817 Fhit-007 protein_coding Mus_musculus 0 366
ENSMUST00000160956 Fhit-004 protein_coding Mus_musculus 0 243

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