C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196781 TLE1 9606 - 9:81583683-81689305 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000376463 TLE1-005 81633469-81687368 protein_coding
  ENST00000376472 TLE1-201 81584184-81688266 protein_coding
  ENST00000376484 TLE1-004 81599865-81613522 protein_coding
  ENST00000376499 TLE1-001 81583683-81689305 protein_coding
  ENST00000418319 TLE1-002 81620454-81688448 protein_coding
  ENST00000464999 TLE1-003 81611843-81620539 processed_transcript
  ENST00000491534 TLE1-006 81611806-81620557 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376463ENST00000376472ENST00000376499
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376463 4.201±0.00 8.016±0.00 7.751±0.00 5.539±0.00 4.410±0.00 1.561±0.00 3.948±1.27 6.141±0.00 2.880±0.00 5.336±0.00 6.766±0.44 4.989±1.37 8.118±1.99
ENST00000376472 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 5.380±0.00 5.320±0.00 4.164±0.00
ENST00000376499 8.915±0.00 6.928±0.00 4.314±0.00 10.961±0.00 13.495±0.00 0.974±0.86 4.371±2.97 3.239±0.00 N/A 4.406±0.00 8.075±1.18 5.242±0.31 12.221±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007KE CIL_0007KE_0002 UCNEbase 9:79125686-82895571
CIL_00090V CIL_00090V_0001 VISTA 9:81094601-81695951
CIL_0008X3 CIL_0008X3_0001 VISTA 9:81252436-81853261
CIL_0009AO CIL_0009AO_0001 VISTA 9:81349280-81952035
CIL_0008C4 CIL_0008C4_0001 VISTA 9:81384295-81985202
CIL_0008TV CIL_0008TV_0001 VISTA 9:81523283-82124424

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001106 IDA RNA polymerase II transcription corepressor activity
GO:0003682 IEA chromatin binding
GO:0003714 IEA transcription corepressor activity
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005829 IMP cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0007165 TAS signal transduction
GO:0007219 TAS Notch signaling pathway
GO:0007275 TAS multicellular organismal development
GO:0008134 IPI transcription factor binding
GO:0009887 TAS organ morphogenesis
GO:0010628 IMP positive regulation of gene expression
GO:0016055 IEA Wnt signaling pathway
GO:0030178 NAS negative regulation of Wnt signaling pathway
GO:0042802 IPI identical protein binding
GO:0043124 IDA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:2000811 IMP negative regulation of anoikis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000067832 TLE6 transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila) protein_coding Danio_rerio
ENSMUSG00000008305 Tle1 transducin-like enhancer of split 1, homolog of Drosophila E(spl) protein_coding Mus_musculus

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