C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info

Description: transducin-like enhancer of split 1 (E(sp1) homolog, Drosophila)
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000376499 TLE1-001 ENSG00000196781 9606 - 9:81583683-81689305 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000376499
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000376499 8.915±0.00 6.928±0.00 4.314±0.00 10.961±0.00 13.495±0.00 0.974±0.86 4.371±2.97 3.239±0.00 4.406±0.00 8.075±1.18 5.242±0.31 12.221±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0007KE CIL_0007KE_0002 UCNEbase 9:79125686-82895571
CIL_00090V CIL_00090V_0001 VISTA 9:81094601-81695951
CIL_0008X3 CIL_0008X3_0001 VISTA 9:81252436-81853261
CIL_0009AO CIL_0009AO_0001 VISTA 9:81349280-81952035
CIL_0008C4 CIL_0008C4_0001 VISTA 9:81384295-81985202
CIL_0008TV CIL_0008TV_0001 VISTA 9:81523283-82124424

Gene Ontology

GO IDEvidence TypeGO Description
GO:0000122 IEA negative regulation of transcription from RNA polymerase II promoter
GO:0001106 IDA RNA polymerase II transcription corepressor activity
GO:0003682 IEA chromatin binding
GO:0003714 IEA transcription corepressor activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IDA nucleus
GO:0005654 TAS nucleoplasm
GO:0005667 IEA transcription factor complex
GO:0005730 IDA nucleolus
GO:0005737 IDA cytoplasm
GO:0005829 IMP cytosol
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006357 IEA regulation of transcription from RNA polymerase II promoter
GO:0007165 TAS signal transduction
GO:0007219 TAS Notch signaling pathway
GO:0007275 TAS multicellular organismal development
GO:0008134 IPI transcription factor binding
GO:0009887 TAS organ morphogenesis
GO:0010628 IMP positive regulation of gene expression
GO:0016055 IEA Wnt signaling pathway
GO:0030178 NAS negative regulation of Wnt signaling pathway
GO:0042802 IPI identical protein binding
GO:0043124 IDA negative regulation of I-kappaB kinase/NF-kappaB signaling
GO:0045892 IDA negative regulation of transcription, DNA-templated
GO:2000811 IMP negative regulation of anoikis

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000072695 Tle1-001 protein_coding Mus_musculus 0 3140
ENSMUST00000074216 Tle1-201 protein_coding Mus_musculus 0 3118
ENSMUST00000102848 Tle1-006 protein_coding Mus_musculus 0 3022
ENSMUST00000132550 Tle1-005 retained_intron Mus_musculus 0 2867
ENSMUST00000030095 Tle1-008 protein_coding Mus_musculus 0 2427
ENSMUST00000052011 Tle4-201 protein_coding Mus_musculus 0 1463
ENSMUST00000167776 Tle4-202 protein_coding Mus_musculus 0 1245
ENSMUST00000159050 Tle3-007 protein_coding Mus_musculus 0 1061
ENSMUST00000107337 Tle1-002 protein_coding Mus_musculus 0 1002
ENSMUST00000162127 Tle3-009 protein_coding Mus_musculus 0 911
ENSMUST00000034820 Tle3-002 protein_coding Mus_musculus 0 911
ENSMUST00000178113 Tle3-201 protein_coding Mus_musculus 0 894
ENSMUST00000159386 Tle3-008 protein_coding Mus_musculus 0 894
ENSMUST00000161207 Tle3-006 protein_coding Mus_musculus 0 894
ENSMUST00000162583 Tle3-005 protein_coding Mus_musculus 0 894
ENSMUST00000161689 Tle3-011 protein_coding Mus_musculus 0 894
ENSMUST00000159630 Tle3-010 protein_coding Mus_musculus 0 894
ENSMUST00000160882 Tle3-003 protein_coding Mus_musculus 0 894
ENSMUST00000162973 Tle3-001 protein_coding Mus_musculus 0 894
ENSMUST00000159140 Tle3-012 retained_intron Mus_musculus 0 878
ENSDART00000100020 gro1-201 protein_coding Danio_rerio 0 850
ENSDART00000130553 gro1-001 protein_coding Danio_rerio 0 850
ENSMUST00000137075 Tle1-007 protein_coding Mus_musculus 0 793
ENSMUST00000134225 Tle1-004 processed_transcript Mus_musculus 0 689
ENSMUST00000123259 Tle1-009 processed_transcript Mus_musculus 0 470

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